Abstract 5886: Diastolic Heart Failure and Sleep Disordered Breathing - a Prevalence Study
In patients (pts) with symptomatic heart failure and systolic dysfunction (systolic heart failure, SHF) a high prevalence of sleep disordered breathing (SDB) has been documented. The purpose of this study was to investigate the prevalence and type of SDB in patients with symptomatic heart failure and diastolic heart failure (DHF). In 252 consecutive pts (89 women, 65.3 ± 1.4 years) with DHF capillary blood gas analysis, measurement of NT-proBNP concentrations, echocardiography, cardiopulmonary exercise testing (CPX), cardiorespiratory polygraphy as well as simultaneous right and left heart catheterisation were performed. SDB was defined as an apnea-hypopnea-index (AHI) ≥ 5/h. Due to the majority of events, patients were classified to have either obstructive sleep apnea (OSA) or central sleep apnea (CSA). SDB was documented in 70% of all pts, 100 pts (40%) presented with OSA and 77 pts (31%) with CSA. Only 75 pts (30%) had no relevant SDB (noSDB). Additional results are presented the table⇓. There is a high prevalence of SDB in patients with DHF. In parallel to pts with SHF, especially those with CSA are characterized by a more impaired cardiopulmonary function, higher NT-proBNP concentrations, larger left atrial diameter, and higher left-ventricular filling pressures. Whether SDB is of prognostic relevance in DHF is currently under investigation.