Abstract 5782: Assessment of Right Ventricular Function by Real-Time 3D Echocardiography Closely Agrees With Magnetic Resonance Imaging
Background and objectives: Due to the complexity of right-ventricular geometry, the value of 2D-echocardiography is limited in determining volumes and ejection fraction. Real-time 3D echocardiography (RT3DE) using a novel software package enables rapid determination of right ventricular size and function. Aim of the study was to validate the new technology using magnetic resonance imaging (MRI) as gold standard.
Methods: 44 patients with normal or pathological right ventricles due to various cardiac diseases (coronary artery disease, valvular heart disease, arrhythmogenic right ventricular cardiomyopathy, myocarditis) were examined by transthoracic RT3DE. After acquisition of a pyramidal data volume, a dynamic polyhedron model of the right ventricle was reconstructed based on the endsystolic and enddiastolic contours at predefined standard cut planes. Right ventricular volumes and ejection fraction were determined and compared with the results obtained by MRI. All measurements were done in a blinded fashion.
Results: Enddiastolic (RVEDV) and endsystolic (RVESV) volumes obtained by RT3DE were lower but correlated well with the values determined by MRI (Table 1⇓). Importantly, no significant differences were found for stroke volume (RVSV) and ejection fraction (RVEF). Bland-Altmann analysis showed slight-to-moderate mean differences in measuring RVEDV (−15±0ml), RVESV (−9±8ml) and RVSV (−5±9ml) but only a small mean difference in the measurements of RVEF (2±%).
Conclusion: RT3DE may become a time-and cost-saving alternative to MRI in the quantitative assessment of the right ventricle. In particular, there is close agreement between the two modalities in the determination of right ventricular systolic function.