Abstract 58: Spontaneous Body Temperature Is Associated With Survival Following In-hospital Cardiac Arrest And Return Of Spontaneous Circulation: A Report From The National Registry Of Cardiopulmonary Resuscitation
Objective- Spontaneous changes in body temperature after cardiac arrest are common, but their association with survival is not known. This study tested the hypothesis that temperature is associated with survival to hospital discharge.
Methods-Included were adults with in-hospital cardiac arrest, enrolled in the National Registry of CPR who achieved return of spontaneous circulation between January 1, 2005 and November 7, 2006. Excluded were those who received induced hypothermia. The lowest (Tmin) and highest (Tmax) body temperature during the first 24 hours after ROSC were included in a multivariable logistic regression predicting survival to hospital discharge, adjusting for variables that were independently associated with outcome. Tdelta was defined as Tmax -Tmin, examined in a separate regression. Goodness of fit was measured using Hosmer-Lemeshow (HL) statistic.
Results- 14,413 subjects were included. Of these, 5,319 (36.9 %) survived to hospital discharge. Tmin and Tmax were available for 8,005 (55.5%) and 7,872 (54.6%) of all patients. Tables⇓ exhibit the odds ratio (95% CI) of survival to discharge by Tmin and Tmax and Tdelta groups.
Conclusions-Spontaneous hyperthermia and hypothermia following in-hospital cardiac arrest is associated with lower odds of survival to discharge. Lability of temperature >1°C is also associated with lower odds of survival to discharge.