Abstract 3665: Changing Age Distribution of First Ever Acute Myocardial Infarction Among Men and Women in New Jersey Hospitals
While the death rate from coronary heart disease has fallen, the occurrence of non-fatal acute myocardial infarction (AMI) has risen, especially among the elderly.
Methods: To study the shift in age distribution of first-ever hospitalized (index) AMI we used two four-year periods, 1986–1989 and 2001–2004 from the New Jersey statewide myocardial infarction data acquisition system, MIDAS. The frequency and age-specific rates were compared for men and women.
Results: There were 60,226 index AMI cases in the 1986–1989 period and 58,901 in 2001–2004. The age distribution curve show a marked shift towards older ages, with a noticeable drop in occurrence among those aged 55 to 70. The median age at which the index AMI occurred rose significantly (p<.0001); from 64 to 66 years of age among men, and from 72 to 77 years of age in women. The number of events occurring below age 85 decreased by 1,511 (7%) in women and by 4,432 (13%) in men. In contrast, for those aged 85 and above the number of events doubled; increasing by 1,732 (110%) in men, and by 2,886 (91%) in women. The rate of index AMI decreased overall, 31% among men, and 24% in women, except in the oldest age group (≥85). For those aged 85 and above the AMI rate increased more in women (by 16%) than in men (by 11%).
Conclusions: The annual occurrence of index AMI has remained stable over the past fifteen years, while the first AMI event has been postponed by 2 and 5 years among men and women respectively. Before age 85 both the number and rate of first AMI events decreased, mostly among men. In contrast among the oldest the increase in events was seen more in women. Among persons younger than 60, however, there appears to have been little change in age at first AMI.