Abstract 3549: Cardiac Rehabilitation Reduces Depression in Coronary Artery Disease Patients
INTRODUCTION: In patients with coronary artery disease (CAD), the prevalence of patients showing significant symptoms of depression is high (35–45%). There is also ample evidence that depression has a negative impact on the morbidity and mortality of those with CAD.
HYPOTHESIS: Patients in cardiac rehabilitation will have an improvement in depression scores utilizing mood scale assessments and those completing 36 visits of cardiac rehabilitation will improve depression scores with or without antidepressants.
METHODS: From 2005–2007 the PRIME-MD(PHQ-9) Mood Scale assessments of 345 cardiac rehabilitation participants were reviewed. Of the 345 charts reviewed, 37% (N=129) scored positively for depression. Of the patients who scored positively, 50 did not complete program, 3 were excluded. The remaining 76 patients were re-screened at program completion and were categorized into two groups: Cardiac Rehabilitation alone (CR) group and Treatment group (T). The CR group (N=62, 35 males and 27 females, age 67±10) participated in cardiac rehabilitation with no other intervention for depression. The T group (N=14, 8 males and 6 females, age 61±14) consisted of patients who received antidepressant therapy along with cardiac rehabilitation.
RESULTS: There was a significant improvement in depression scores in both the CR group (8.1±3.9 to 3.5±3.7, p<0.0001) and in the T group (11.0±5.8 to 7.2±6.9, p<0.001), however there was no difference in improvement of depression scores between the CR group and the T group (p=NS).
CONCLUSIONS: CAD patients who screened positively for depression significantly improved their depression scores by completion of program. There was no significant difference in depression score improvements between those who participated in the CR group and those who were in the T group. These data suggest that the exercise, lifestyle intervention education, and social atmosphere of a structured cardiac rehabilitation program can be an effective non-pharmaceutical approach to the treatment of depression in the cardiac patient.