Abstract 3349: A Flow-guided Concept To Treat Side Branches In True Bifurcation Lesions: A Randomized Clinical Study - Thueringer Bifurcation Study, THUEBIS-Study
Background The therapy of bifurcation lesions is a unsolved problem.
Methods We initiated a controlled prospective randomized trial and included all patients with bifurcation lesions. Pts were randomized into two therapeutic options: Stenting of the main branch (MB, Taxus-stent, PES) + mandatory SB-PCI (kissing-balloons) with provisional side branch (SB) stenting (therapy A) or stenting of the main branch (Taxus-stent) with provisional SB-PCI only when the SB had a TIMI flow < 2 or angina (therapy B).
Results We included 110 pts. Mean follow up was 6.1 months. Results are given in tables 1⇓ and 2⇓. Final TIMI flow 3 (MB) was reached in all pts (group A and B), stent diameter or -length (MB) were not different in both groups. Mean radiation time (min) and mean amount of contrast media (ml) was 14.2/210 (A) vs. 7.8/151.6 (B) (p for both < 0.05). Peak troponin I 24 h after PCI was 4.0 (A) vs. 2.4 ng/ml (B, p= 0.6).
Follow-up FU-data are shown in table 3⇓. In group B, no PCI of the SB was done during FU.
Conclusion A simple strategy using PES with only provisional SB-PCI is not inferior to a more complex strategy with mandatory SB-PCI.