Abstract 3100: Quantitative MR Reference Values For Cardiac Adaptation To Physical Training
Purpose: Under 40 years of age most sudden cardiac death in athletes is caused by cardiomyopathy. Differentiation between an athletes heart and cardiomyopathy is often difficult on cardiac MRI (CMR) due to overlap in cardiac dimensions. This is especially true for the right ventricle as MR and echocardiographic reference standards are limited. Accurate reference values (upper limits of normal) of physiological adaptation of the heart in athletes are necessary to ensure a correct diagnosis, and to avoid missing cardiomyopathies or unnecessary exclusion from competitive sport.
Methods: 165 endurance athletes (18 – 40 years old; > 9h exercise per week) and 140 age and sex matched healthy controls have been included in this ongoing study. Preliminary results of the first 70 athletes and 40 controls (36% women, mean age 26.5 years ± 7,24) are presented. All subjects underwent 1.5T cardiac MRI, echocardiography, ECG and an extensive questionnaire. Blinded observers experienced in CMR data analysis performed quantitative measurements which were indexed for body surface area with the Dubois and Dubois method.
Results: Results for the left and right ventricle are presented in the table⇓.
Conclusions: Volumes and masses are increased in both ventricles of the athlete’s heart. Completion of analysis of all participant data will establish reliable reference CMR values to assist in the differentiation between an athletes heart and cardiomyopathy.