Abstract 3854: One-Year Cardiovascular Hospitalization Rates and Health Care Costs in Patients at Risk for Atherothrombosis: Results from the REACH Registry
Background: Atherothrombosis, the leading cause of death worldwide, exacts a high economic toll. REACH is an international prospective registry in patients at risk of atherothrombotic (ATH) events due to coronary artery (CAD), cerebrovascular (CVD) and/or peripheral arterial disease (PAD), or ≥ 3 ATH risk factors (RFs).
Methods: Using U.S. data from REACH, we examined 1-year rates of hospitalizations (HOSPS) for vascular reasons, and 1-year costs, including HOSPS and medications (MEDs), across patient subgroups. HOSPS were assigned DRGs and associated MedPAR 2004 average costs. MEDS were costed using 2004 Red Book prices. Baseline predictors of total costs were examined using linear regression.
Results: CHF, unstable angina, MI and stroke were the most common reasons for HOSP for both symptomatic (rate per 1000 pts:44,43,25,21) and asymptomatic (rate per 1000 pts: 13.2, 12.2, 8.4, 8.8) patients, and vascular intervention rates were high. Like hospitalization rates, total costs increased with # vascular beds (VBs; β = $2348,p < .0001) affected. Other predictors of costs include age < 65 yrs (β = $569,p < .0005), hypertension (β = $908,p < .0001), diabetes (β = $1963,p < .0001) and hypercholesterolemia (β = $814,p < .0001).
Conclusion: HOSPS and costs increase dramatically with each additional VB. Efforts are needed to reduce high event rates and treatment costs in atherothrombotic patients.