Abstract 3822: Multislice Computed Tomography and Exercise Electrocardiography for Detection of Coronary Artery Disease: Intraindividual Comparison with Conventional Coronary Angiography
Objectives: To prospectively analyze whether multislice computed tomography (MSCT) is superior to exercise electrocardiography (Ex-ECG) for diagnosis of coronary artery disease with conventional coronary angiography as the reference standard.
Methods: A consecutive cohort of 80 patients with suspected coronary artery disease was examined with MSCT using 16 * 0.5 mm detector collimation, exercise ECG, and conventional coronary angiography according to standard protocols. Results were compared using the paired McNemar’s test, the chi-square test, and 95% confidence intervals (CIs).
Results: Both the sensitivity and specificity of MSCT (91% [40 of 44 patients, 95%CI: 78–97%] and 83% [30 of 36 patients, 95%CI: 67–94%]) were significantly higher (P=0.039 and P<0.001) than those for Ex-ECG (73% [32 of 44 patients, 95%CI: 57–85%] and 31% [11 of 36 patients, 95%CI: 16–48%]). The pairwise McNemar’s test showed significant differences between MSCT and Ex-ECG in the overall diagnosis in patients with suspected coronary artery disease (P=0.036). The rate of non-diagnostic examinations was not significantly (P=0.078) different between MSCT and Ex-ECG (8% [6 of 80 patients, 95%CI: 3–16%] vs. 19% [15 of 80 patients, 95%CI: 11–29%]).
Conclusions: In this consecutive cohort of patients scheduled to undergo conventional coronary angiography, the performance of MSCT for diagnosis of coronary artery disease was superior to that of Ex-ECG.