Abstract 3765: Differences in the Prevalence of Atrial Fibrillation and Flutter in Hispanics and Whites in a Large Community Heart Failure Population
Objective & Background: Significant racial/ethnic differences in AF prevalence have been reported between African Americans and whites. We sought to determine if the prevalence of atrial fibrillation and flutter (AF) differed significantly between Hispanics and whites in patients in heart failure (HF).
Methods: We identified 6,180 persons with a primary HF hospitalization in a large integrated health care delivery system from January 1999 to March 2005. Multiple logistic regression models yielding odds ratio (OR) and 95% CI were used to explore the independent relationship between ethnicity/race and AF. Models were validated using the Goodness of Fit test described by Hosmer and Lemeshow.
Results: The cohort consisted of 1,395 Hispanics and 5,281 whites. The mean age was 73 ±12yrs, and 47% were female. Hispanics were younger than whites (67 ±13 vs. 74 ±12, p<0.0001), and were more likely to have diabetes (63% vs. 45%, p<0.0001) and end stage renal disease (14% vs. 4%, p<0.0001). CAD, hypertension, rheumatic heart disease, and history of valvular surgery or valvuloplasty were similar between groups (p=NS). Caucasians were more likely to have COPD (11% vs. 20%, p<0.0001), and hyperthyroidism (2% vs. 3%, p=0.008). Numerical EF was available for 33% in both groups, with whites having a slightly higher EF (0.43 ±0.17 vs. 0.41±0.16, p=0.02). Multiple logistic regression models for race and AF with whites as referent follow:
Conclusions: In this large cohort of insured patients with HF, Hispanics were substantially less likely to have AF compared to whites even after adjusting for known AF risk factors, deprivation status, and medications.