Abstract 3740: Natural History and Determinants of Right Ventricular Dysfunction After Acute Pulmonary Embolism Assessed by Strain Rate Echocardiography
Aim of the study was to assess global and regional right ventricular (RV) function after acute pulmonary embolism (APE) and to investigate the determinants of acute and chronic right ventricular RV dysfunction.
Methods: Echocardiography with tissue Doppler and strain rate imaging (TDE/SRI) of basal, mid-wall and apical segments of free RV wall was performed in 66 consecutive patients with non-fulminant APE confirmed by computer tomography (CT). Peak values for systolic strain rate (SRs ) and strain (Smax ) were determined for each RV segment and given as mean value between the 3 RV segments. RV dysfunction was defined as bidimensional RV ejection fraction (EF) < 50% on apical 4-chamber views. Six-month follow-up was completed in 33 of 66 patients.
Results: Predictors of acute RV dysfunction found in 31 patients are given in Table 1⇓. At follow-up, regional and global RV function improved significantly in the subgroup with previous acute RV dysfunction (Table 2⇓).
Impaired long-axis RV regional deformation is the underlying mechanism of acute RV dysfunction after APE.
At 6-month follow-up, RV global and regional function recovered in patients presenting formerly with acute RV dysfunction. Moreover, no late dysfunction occurred in the group with normal RV EF after APE.
TDE/SRI is a useful tool to assess the extent and mechanisms of RV dysfunction after APE.