Abstract 3667: Comparison of Coronary Collateral Flow Between Stable and Unstable Angina Pectoris
[Background] The coronary collateral flow has important roles in patients with ischemic heart disease. It is established that Qc/QN ,which is the index of collateral flow, were good and independent predictors of the function of collateral vessels producing complementary information. However, the implication of coronary collateral flow in patients with stable angina pectoris (SAP) and unstable angina pectoris (UAP) remains unclear.
[Object] The aim of this study was to evaluate whether there is difference in coronary collateral flow between SAP and UAP.
[Methods] Fifty patients with angina pectoris (SAP; n=30, UAP; n=20) undergone percutaneous coronary intervention were enrolled. Fractional flow reserve (FFRmyo) and Qc/QN were determined by pressure wire and were compared between the patients with stable unstable angina pectoris. [Results] Clinical characteristics ,the degree of angiographic stenosis (78±8 VS 81±6) and FFRmyo (0.56±0.08 VS0.45±0.09) were not significantly different between the patients with SAP and UAP. Although there was a significant inverse correlation between FFRmyo and Qc/QN in patients with SAP (r=-0.76), no correlation was obtained in patients with UAP. Thus, good collateral flow could be expected physiologically in proportion to the degree of ischemia in patients with SAP. Qc/QN in patients with UAP was significantly lower than that in patients with SAP (0.18±0.04 vs. 0.24±0.07, p<0.05).
[Conclusion] The coronary collateral flow was significantly lower in UAP compared with SAP. The poor collateral flow might play an important role of iscemic attack in patients with UAP.