Abstract 3638: Intima Media Thickness of Brachial, Femoral and Carotid Arteries: a Sonographic Comparison
Background: Previous studies have shown that sonographicaly measured intima media thickness of either carotid (CIMT), brachial (BIMT) and femoral (FIMT) arteries are correlated with coronary artery disease (CAD). Whether there is a relation of IMT among these 3 different vessels has not been investigated.
Methods: IMT was measured in 60 consecutive male patients (mean age 62±9 years) undergoing coronary angiography (CAG) due to chest pain and/or positive stress test. In 40 patients (68%) coronary artery disease was found. IMT was measured using high resolution ultrasound (BIMT: 13 MHz; CIMT: 8 MHz; FIMT: 11.5 MHz) in zoom mode. BIMT was measured in the right and left cubital region. The CIMT measurements were performed in the right and left common carotid artery 1–2 cm proximal of the carotid bulb. FIMT was assessed in the right and left femoral artery 1–2 cm proximal of the bifurcation with the profound femoral artery. Measurements in the far wall of each vessel were performed off-line by an investigator blinded to the clinical diagnosis. The mean of 3 measurements, performed in close vicinity to each other, was calculated.
Results: The mean IMT values in BIMT, FIMT and CIMT were 0.31±0.05mm, 0.56±0.16mm and 0.7±0.14mm, respectively. No differences in IMT values were found between left- and right-sided vessels. A correlation was found between BIMT and FIMT (r=0.41, p=0.003) but not between FIMT and CIMT and BIMT and CIMT.
Conclusion: This is the first study investigating the correlation of IMT in 3 major arterial beds. A good correlation between IMTs of the arteries of the extremities was found, whereas no relation was seen in IMT of arteries of the extremities and the carotid artery. This finding may suggest different forms of progression of atherosclerosis in the carotid versus peripheral arteries.