Abstract 3268: Prognostic Value of Multi-slice Computed Tomography Coronary Angiography in Patients with Known or Suspected Coronary Artery Disease
Objectives: Data on prognostic value of Multi-Slice Computed Tomography (MSCT) coronary angiography are currently not available. The objective of the study was to determine the prognostic value of MSCT coronary angiography in patients with known or suspected Coronary Artery Disease (CAD).
Methods: One hundred patients (73 men, age 59±12 yrs) underwent MSCT coronary angiography to evaluate the presence and severity of CAD. Patients were followed for the occurrence of cardiac death, non-fatal myocardial infarction, unstable angina pectoris requiring hospitalization and revascularization.
Results: CAD was detected in 80 (80%) patients. During a mean follow-up of 16 months, 33 events occurred in 22 patients. In patients with no CAD, annual event rate was 0% vs 25% in patients with CAD. Event rate was highest in the presence of obstructive lesions (50%) and when obstructive lesions were found in the left main/left anterior descending coronary arteries (65%). Elevated event rate was also observed in patients with non-obstructive CAD (8%) (Figure 1⇓). MSCT characteristics as predictors of events were identified on multivariate Cox regression analysis (Table 1⇓). Figure 1⇓. Kaplan-Meier curves for all events.
Conclusions: MSCT coronary angiography provides independent prognostic information in patients with known and suspected CAD. Excellent prognosis was noted in patients with a normal MSCT.