Abstract 3228: Complete Revascularization to the Pedal Arch May Improve the Survival of Patient with Critical Limb Ischemia
Background: Five-year survival of patients with peripheral artery disease presenting critical limb ischemia (CLI) is as poor as 40–50%. Recent advancement of the endovascular techniques has enabled complete revascularization to the pedal arch, thereby improving the limb salvage rate in CLI. However, whether the complete revascularization improves the survival in patients with CLI remains unknown. We sought to delineate the factors influencing the mortality of patients with CLI in the era of advanced endovascular revascularization.
Method: Consecutive 109 patients with CLI complaining of non-healing ulcer defined as Rutherford VI or V were enrolled between March, 2001 and April, 2006 and were followed up for 37±12month. Multivariate analysis was performed to explore the independent determinants of mortality.
Results: Death occurred in 29 patients during the follow up. Male gender, aged >80 years, ankle brachial index <0.6, hypertension, diabetes mellitus, dialysis treatment, coronary artery disease, cerebral vascular disease, multiple lesions, and complete revascularization to the pedal arch were chosen as independent variables related to mortality by single regression analysis. Among these, complete revascularization was the strongest independent factor associated with the mortality by multivariate analysis (Table⇓). Patient characteristics and lower limb status were similar between patients with and without complete revascularization.
Conclusion: Complete revascularization to the pedal arch yields independent prognostic significance among patients with CLI in this retrospective study