Abstract 3103: Integrated 3-Dimensional Electromechanical Navigation and Intracardiac Echocardiography with Custom Devices Produced in an NIH Bioengineering Research Partnership Grant Program
Background: Our program has produced EP-enabled intracardiac imaging technology producing high resolution ultrasound imaging and EP recording. We have now integrated it with electro-field navigation so widely used in EP procedures.
Methods: In this series of pre-clinical studies, the combination of the NavX electro-field localization and integration of intracardiac imaging was applied in three closed-chest pigs who underwent intravenous cannulation with both the hockeystick 64-element side-looking steerable phased array catheter, the NavX reference catheter and an EP ablation catheter. The hockeystick is enabled with electrodes proximal and distal to the imaging port. This allows the imaging catheter as well as the ablation catheter to be located in 3D space relative to each other and assists in positioning of the ultrasound image field and the ablation catheter and allow overlay of images into the 3D shell.
Results: Navigation and manipulation time for achieving ultrasound imaging of ablation was substantially reduced; by over 75% compared to fluoroscopic visualization only, which was used in one pig. The ablation catheter tip and ablation changes in the surrounding tissue, including bubbles and heating changes could be observed with the EP signals from the region superimposed over the images.
Conclusions: These unique pre-clinical studies demonstrate a spatially accurate 3-dimensional navigation environment for the use of intracardiac imaging as an adjunct to both EP testing and ablation procedures.