Abstract 3052: Side Branch Stenting as a Major Predictor of Mid-Term Clinical Adverse Outcome After Percutaneous Coronary Intervention in Unprotected Left Main Bifurcation Lesions: A Multivariate Analysis
Background: Optimal approach when stenting bifurcation lesions is still not clear, moreover in the setting of distal left main (LM) bifurcation. Evidence whether side branch should be stented or not is lacking. Objective of this study was to evaluate the impact of side branch stenting on outcome.
Methods: A subset of 179 consecutive patients included in the Left Main TAXUS Pilot study and treated for distal left main (LM) bifurcation lesion between March 2003 and June 2005 has been analyzed. We performed univariate and multivariate analysis to identify predictors of MACE.
Results: At median FU of 8.5 months MACE occurred in 29/179 patients (16%). Variables accounted for in the test were: age, EF, general risk factors, presence of 3-vessel disease, ACS at baseline, angiographic variables (including severity of disease in the main and side branch) before and after PCI and stenting of side branch. Variables differing in the two groups with a p<0.10 were entered in logistic regression multivariate analysis.
Conclusions: The only independant predictors of MACE after PCI of unprotected LM are diabetes, hypertension, side branch stenosis and side branch stenting.