Abstract 3032: Assessment of Right Ventricular Volumes, Mass and Ejection Fraction by Matrix Array Three-Dimensional Echocardiography in Pediatric Patients with Congenital Heart Disease: A Comparison with Magnetic Resonance Imaging
Introduction: Due to complex and asymmetric geometry, non-invasive of right ventricular volume (RVV) by 2-D imaging in pediatric patients with congenital heart disease (CHD) has been limited. Three-dimensional echocardiography (3DE) allows measurement of RVV by summation of discs, without geometric assumptions. Matrix array, real-time, 3DE obtains full volume acquisitions of entire RV in 4 beats, obviating motion artifact. The purpose of this study was to compare measurements of RVV, mass (M) and ejection fraction (EF) by matrix array 3DE in pediatric patients with CHD patients and compare to simultaneous measurements by MRI.
Methods: 15 patients with pediatric patients with CHD (median age 36 month (range 9–94) undergoing cardiac MRI under general anesthesia were prospectively enrolled. To ensure similar loading conditions, matrix array 3DE (Sonos 7500, Philips) acquisitions using sub-costal probe placement were performed immediately after MRI. 3DE datasets were analyzed without knowledge of the MRI results by two blinded observers using off-line summation of discs methods (Tomtec), and compared to MRI summation of discs.
Results: Results are shown as mean +/− SD
Conclusion: 3DE EDV and ESV correlated well with MRI, but had consistently lower values. 3DE mass and EF also correlated well with MRI with good agreement. 3DE inter-observer variability was excellent for all 3DE measurements. Results of this study demonstrate that matrix array 3DE is clinically applicable for the serial assessment of RV size and function in pediatric patients with CHD.