Abstract 2473: Race and Gender Differences in Post-Procedural Outcomes Following Percutaneous Coronary Intervention in African Americans and Caucasians
Background: Outcomes assessment by race and gender after PCI have separately compared African Americans (AA) to Caucasians (CA) and females to males, but no study has concentrated on a combined outcomes analysis of both race and gender in the current PCI era.
Methods: We analyzed 654,022 PCIs within the American College of Cardiology National Cardiovascular Data Registry from 1/1/2001 to 12/31/2004. Baseline characteristics and in-hospital post-procedural outcomes in AA (n=35,173) were compared to CA (n=618,849); and, CA females (n=207,076), AA males (n=18,910), and AA females (n=16,263) were compared to CA males (n=411,773).
Results: Despite baseline clinical differences between AA and CA patients, no difference in adjusted mortality was observed between races following PCI (OR 0.85; 95% CI 0.76 –1.05; p=0.21). However, relative to CA males, AA females had a 16% higher adjusted mortality rate (1.50% vs. 1.30%). Furthermore, CA females (1.43%) and AA males (1.40%) had significantly higher mortality rates compared to CA males (10% and 7.7% higher than CA males, respectively). Additional adjusted outcomes by race and gender are listed in the figure⇓ below.
Conclusion: No difference in mortality was observed by race alone. However, race and gender analyses showed clear differences with African American females carrying the highest adjusted-risk for mortality and Caucasian females most likely to have peri-procedural complications. These results highlight the importance of considering both race and gender in peri-PCI risk assessment, and underscore the need for targeted interventions in these high-risk groups to improve their peri-procedural outcomes.