Abstract 2470: Are Drug-Eluting Stents (DES) Indicated in Large Coronary Arteries? Insights from a Multi-Centre Victorian Percutaneous Coronary Intervention (PCI) Registry
Background: It is current practice in many Australian and New Zealand hospitals to restrict drug-eluting stents (DES) to smaller vessels. The aim of this study was to evaluate outcomes after implantation of ≥3.5mm DES compared with bare metal stents (BMS).
Methods: We studied 610 consecutive patients who had a ≥3.5mm diameter stent deployed. All patients were part of a large ongoing MIG PCI registry from 7 Victorian public hospitals enrolled from April 2004 to January 2006. Outcomes were analysed in the 507 and 119 patients who were eligible for follow up at 30 days and 1 year respectively. 400 patients will be eligible for 1year follow up August 2006.
Results: The mean age ± SD was 64.6 ± 12.0 years. Females comprised 22.1%, diabetics 20.1% and 63% had an acute coronary syndrome. The target vessel was the LAD in 25.3%. DES comprised 36.1% of PCI using ≥ 3.5mm stents.
Conclusion: Deployment of ≥ 3.5mm diameter stents in large coronary arteries is associated with low rate of mortality and major adverse cardiac events (MACE) at 30 days and 1 year irrespective of DES or BMS use. Findings will be confirmed and refined with as more patients are eligible for follow up.