Abstract 2426: Relationship Indicators of Carotid and Left Main Coronary Artery Atherosclerosis by Ultrasound and the Number of Coronary Artery Disease
Background: It has been demonstrated that the mortality rate, additional intervention, and prevalent angina were lower in single vessel disease patients (SVD), compared to multi vessel disease patients (MVD). Little has been reported on the relationship between progression of coronary artery disease and carotid or left main coronary artery atherosclerosis. The aim of this study was to evaluate the association between the number of coronary artery disease and indicators carotid plaque by ultrasonography and left main coronary artery (LMCA) plaque by intravascular ultrasound (IVUS).
Method: This study consisted of 55 consecutive patients had significant coronary artery stenosis. They were divided into two groups: 18 patients with SVD, 37 with MVD. In the all patients, carotid artery was examined by ultrasonography and LMCA by IVUS. At the carotid artery, plaque area, calcium length, and number of plaque were measured, and maximum intima-media thickness (max-IMT) was computed as the thickness grater than or equal to 1.1mm, using longitudinal scan. At the LMCA, with volumetric IVUS analysis, external elastic membrane area (EEMA), lumen area (LA), plaque area (PA) and the angle of the calcium were measured at each cross-section 1mm interval. The volume of EEM, lumen, plaque, and calcium arc were calculated. To adjust for different LMCA length, volume index (VI) was calculated as volume data divided by LMCA length.
Results: Conclusion This study suggest that carotid plaque number, carotid calcium length and LMCA average calcium angle might be independent predictors of multi vessel disease and confer additional prognostic value and guide clinicians in cardiovascular assessment.