Abstract 2013: New Onset Atrial Fibrillation is an Independent Predictor of In-Hospital and Short Term Mortality in Patients Admitted with Heart Failure. Results of the Euro Heart Failure Survey
Background: The prognostic significance of atrial fibrillation (AF) in patients admitted due to heart failure (HF) remains poorly understood. Objective: To evaluate in what way AF, and its different presentations, affect in-hospital mortality in patients admitted with HF.
Methods: The Euro Heart Failure Survey was conducted to ascertain how hospitalized HF patients are managed in Europe. The survey enrolled 10701 patients over a 6-week period in 115 hospitals from 24 countries belonging to the ESC. For this analysis patients were divided in 3 groups according to the type of AF; persistent-AF (patients with known history of AF), new onset-AF (no history of AF with AF diagnosed during hospitalization) and no-AF (no history of AF and no AF during hospitalization). Clinical variables, duration of hospitalization, in-hospital and short term (12 week) survival status were assessed and compared among groups.
Results: Table 1⇓ summarises the clinical characteristics and in-hospital evolution of the different groups. In the univariate analysis the type of AF (but not the presence of AF), fast AF (>120 beats/min ), age, female gender, ejection fraction (EF), moderate or severe left atrial (LA) dilatation, use of antiarrhythmic drugs (AAD) and inotropic treatment were predictors of mortality. When including these variables in a multivariate model, new onset-AF (not fast AF) remained an independent predictor of in-hospital and (OR 1.5 [CI, 1.1–2.0]) 12 week mortality (OR 1.5 [CI, 1.2–1.7])
Conclusion: In patients admitted with HF new onset AF is an independent predictor of in-hospital and short term mortality.