Abstract 1951: Impact of Number of Stents and Stented Length as Predictors of Repeat Revascularization: A Report from the DEScover Registry
Background: Complete lesion coverage with drug-eluting stents (DES) is common in contemporary interventional cardiology. While the number of implanted stents and the total stented length were predictors for repeat revascularization in the bare-metal stent era, whether this is true with DES is less well established. We investigated the role of number of stents and total stented length as predictors of repeat revascularization in the contemporary DEScover Registry.
Methods: Among 7752 patients enrolled in the Registry, 4793 subjects with single-vessel interventions with DES were identified. The subjects were stratified by the number of stents placed (1, 2 or ≥ 3) and by quartiles of stented length (32 mm). Saphenous vein graft interventions were excluded. Six-month clinical outcomes included repeat revascularization, stent thrombosis, MI, and death.
Results: Mean age of subjects was 63 years with 34% female. Indication for percutaneous revascularization included acute MI (24.8%), unstable angina (30.4%), and elective (37.3%), and there were no differences in indications within the stratified groups. There were no significant differences in cardiovascular risk factors or in 6-month outcomes of stent thrombosis, death or MI based on stent length or number of implanted stents. While unadjusted analysis revealed that stented length of > 32 mm and stent number > 1 were both predictors of repeat revascularization, adjusted analysis suggests that any number of implanted stents > 1 was more predictive of repeat revascularization than stented length alone (table⇓).
Conclusions: The analyses suggest that when using drug-eluting stents, the number of implanted stents may be more significant than the total stented length in treating a single coronary lesion in terms of need for repeat revascularization. Further analyses are needed to decipher the independent effect of stented length versus number of stents in predicting repeat revascularization.