Abstract 1897: Short and Long Term Effect of Diabetes on Mortality in Subjects with Peripheral Arterial Disease
Background: Peripheral arterial disease (PAD) is associated with increased risk of mortality from cardiac causes and frequently accompanies diabetes (D). We compared long term mortality in PAD subjects with and without D.
Methods: All subjects discharged from any VA Medical Center between 10/90–9/97 with an ICD-9 code for PAD and D in the discharge summary were identified. Demographic data were extracted from the database. Mortality data was obtained from Beneficiary Information and Resource Locator.
Results Of 33.629 patients with PAD, 9474 (29%) had D. D subjects were less likely to be white (77% vs 82% p<0.001), older (67vs 66.7 yrs, p=0.005) and have greater co-morbidties-hypertension, coronary disease, congestive heart failure and hyperlipidemia (all p<0.001) except smoking. Mean length of hospital stay was greater for D ( 22.3 days vs 18.7 days, p<0.001). While 60 day mortality was no different (3.1% vs 3.0%, p=NS), mortality was higher for D at 180 days (9.8% vs 8.4%, p<0.001) , 1 year (16.4% vs 13.7%, p<0.001) and continues to increase at 8 years of follow-up.(Figure⇓).
Conclusions: D increases all cause mortality in subjects with PAD starting at 6 months post discharge and continues to be high even at 8 years of follow up.