Abstract 1886: Prevalence and Prognostic Value of Intramyocardial Late Gadolinium Enhancement in Dilated Cardiomyopathy
Background: Late-gadolinium enhancement(LGE) cardiovascular magnetic resonance (CMR) has emerged as an useful diagnostic tool in the assessment of cardiomyopathies, but its prognostic value still needs to be stablished. Up to 30% of patients with dilated cardiomyopathy (DCM) have intramyocardial LGE. We evaluated the prevalence and prognostic value of the presence of intramyocardial LGE in patients with DCM.
Methods: Ninety three consecutive patients with DCM, were divided into to groups in relation to the presence or absence of intramyocardial LGE and followed prospectively for 498 days (28–1884). The primary endpoint was a composite of cardiac mortality and hospitalization.
Results:Intramyocardial LGE was present in 19 patients (20,4%) and this was associated with a higher rate of events, after adjustement for anemia, ACEI treatment and renal failure (adjusted HR 3.24, CI 95% 1.293– 8.119)(see figure⇓).
Conclusion:In our study up to 20% of patients with DCM have intramyocardial LGE.and its presence is a predictor of the composite event of cardiac death and hospitalization. This suggests that intramyocardial LGE has a potencial role in risk stratification of DCM patients.