Abstract 1818: Medium Term Outcomes of Coronary Artery Bypass Graft Surgery On vs Off pump: Result From a Randomized Controlled Trial
Objective: Despite the proposed advantages of off pump CABG surgery some controversy remains as to its advantages compared to on pump CABG. The present study evaluates medium term outcomes from patients that have been randomized to CABG surgery performed on vs off pump.
Methods: All consecutive patients enrolled into a previously completed randomized trial comparing CABG surgery performed on (n = 150) vs off (n = 150) pump were included. The analysis was performed on an intention to treat basis. The outcomes of interest were all cause mortality and readmission to hospital for cardiac reason.
Results: The in-hospital outcomes were excellent in both group with a mortality rate of 0.7% in the on vs 1.4% in the off pump group (p = 0.55). Median follow up was 1.6 years (IQR 1.1 to 2.2 years) with one patient lost to follow-up (99% complete). There were 8 late deaths which were not statistically different between groups and resulted in a greater than 95% survival at 2 years. Freedom from readmission to hospital for cardiac reason was also not statistical different between the two groups with 90% event free survival at 2 years. Multivariate analysis failed to identify the type of procedure (on vs off pump) as an independent predictor of adverse cardiovascular event (mortality + readmission to hospital).
Conclusions: We have shown that in patients randomized to CABG surgery performed on vs off pump excellent medium term results can be obtained with either technique. We have been unable to demonstrate that one technique is superior to the other.