Abstract 1764: Rapid Induction of Percutaneous Cardiopulmonary Bypass Significantly Improves Neurological Function in Patients with Out-of-Hospital Cardiogenic Cardiopulmonary Arrest Refractory to Advanced Cardiovascular Life Support
Objectives: Percutaneous cardiopulmonary bypass (PCPB) is a powerful tool for rescuing the emergency patients (pts) with out-of-hospital cardiogenic cardiac arrest (OHCCA), who are not responding to advanced cardiovascular life support (ACLS). There are few reports investigating the relationship between survival rate in pts with OHCCA and timing using PCPB. The aims of this study were to determine whether rapid induction of PCPB could improve prognosis and neurological recovery in pts with OHCCA at an emergency department.
Methods: In 144 pts with OHCA treated with PCPB in a single institution, 101 consecutive pts with cardiogenic cardiac arrest refractory to ACLS, who had been treated with PCPB, were included. Pts were divided into two groups. Rapid groups (n = 40) were treated by PCPB within 60 minutes after cardiac arrest(CA), and late groups (n = 61) were treated more than 60 minutes after CA. Rate of return of spontaneous circulation (ROSC), weaning of PCPB, survival to discharge, and favorable neurological recovery were assessed.
Results: Rapid groups showed increases in ROSC, weaning of PCPB, survival to discharge, and significant increases in favorable neurological recovery compared to late groups.
Conclusions: These results suggest that the rapid induction of PCPB within 60 minutes after cardiac arrest significantly improves the neurological function in pts with OHCCA.