Abstract 8: Clinical Application of Mild Therapeutic Hypothermia - the European Resuscitation Council (ERC) Hypothermia after Cardiac Arrest Registry (HACA-R)
Background Post-resuscitative mild hypothermia lowers mortality, reduces neurological impairment after cardiac arrest and is recommended by the International Liaison Committee on Resuscitation (ILCOR). The ERC Hypothermia After Cardiac Arrest-Registry (HACA-R) was founded to reflect the state of the art in the use of hypothermia in the post-resuscitative care of patients suffering cardiac arrest within Europe.
Methods Cardiac arrest protocols according to ,,Utstein style“, with additional protocols on cooling and re-warming procedures and possible adverse events are documented. Results Between March 2003 and June 2005 data on 650 patients from 19 sites were entered. Of all patients, 462 (79 percent) received therapeutic hypothermia, 347 (59 percent) were cooled with an endovascular device, 114 (19 percent) received other cooling methods like ice packs, cooling blankets, and cold fluids. The median cooling rate was 1.1°C per hour. Of all hypothermia patients, 15 (3 percent) had an episode of hemorrhage and 28 patients (6 percent) had at least one episode of arrhythmia within 7 days after cooling. Therapeutic hypothermia could not be identified as cause of any serious adverse events.
Conclusions Our study showed therapeutic hypothermia in clinical practice is feasible and can be safely and effectively used. The rate of adverse events was lower compared to preceding randomized controlled trials while cooling rates were quicker.