More Potential for Sildenafil Than Potency
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Sildenafil (Viagra) has the reputation of a typical lifestyle drug. Already, Philip Roth has introduced it to the American literature as such in his novel, The Human Stain, in which the hero, Coleman Silk, a 70-year-old retired college professor, takes his regular Viagra before meeting his girlfriend, who is half his age.1 Given that we are being bombarded by spam e-mail messages advertising sildenafil and other drugs in its group for cheap but uncontrolled sale, one is pleased to find a serious trial on a new indication for this substance in the current issue of Circulation.2
Article p 2980
Sildenafil was applied to patients with therapy-resistant Raynaud’s phenomenon (ischemic finger attacks) in a randomized, placebo-controlled study for 4 weeks in a dose of 50 mg twice daily. The authors report their results on 16 patients with severe secondary Raynaud’s phenomenon (mean age 49 years, range 22 to 74 years, 15 females) associated with …