The Circulatory Effects of Reserpine
The effects of large doses of reserpine have been compared in hypertensive and normotensive patients. The falls of blood pressure are larger in the hypertensives than in the normotensives. In normotensive animals small falls of blood pressure occur. Evidence is presented which suggests that the fall of blood pressure in animals is in part mediated through the sympathetic nervous system. There seems also to be a direct vascular action in animals. In man, evidence is presented which suggests that part at least of the hypotensive action is mediated through the sympathetic nervous system.
- © 1955 American Heart Association, Inc.