Household Clustering of Hypertrophic Cardiomyopathy
A 44-year-old-man had the diagnosis of hypertrophic cardiomyopathy since a murmur was detected during a college physical examination. At age 34, he was successfully resuscitated from ventricular fibrillation, after which a cardioverter-defibrillator was implanted. Thereafter, he had stable exertional angina and dyspnea while taking atenolol and verapamil. A household contact developed dyspnea and lethargy due to heart failure. An echocardio- gram was obtained (Figure 1), demonstrating hypertrophic cardiomyopathy, with marked thickening of the interventricular septum and posterior wall of the left ventricle. The household contact (Figure 2) improved on diltiazem and furosemide, once again catching mice and an occasional rabbit.
Hypertrophic cardiomyopathy is the most common cardiac disease observed in cats. The feline form serves as an animal model of the human disease.
The editor of Images in Cardiovascular Medicine is Hugh A. McAllister, Jr, MD, Chief, Department of Pathology, St Luke’s Episcopal Hospital and Texas Heart Institute, and Clinical Professor of Pathology, University of Texas Medical School and Baylor College of Medicine.
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