In abstract No. 810, “Changes on Right Ventricular Filling in Patients with Carcinoid Syndrome,” which appeared in the Scientific Sessions 2001 abstracts supplement (Circulation. 2001;104(suppl II):II-168), the order of the authors was incorrect. The corrected abstract appears below.
Changes on Right Ventricular Filling in Patients with Carcinoid Syndrome. Ioannis Moyssakis, Nickolaos John Pantazopoulos, Youssef Hallaq, Vasilios Votteas, Michael Kyriakidis, Laiko Hosp, Athens Greece Background: Cardiac involvement is a well-established complication in carcinoid syndrome. The aim of this study was to evaluate the right ventricular diastolic function in patients with carcinoid syndrome without obvious cardiac involvement, and also its relation to urinary 5- HIAA concentrations. Methods: Forty-seven patients (21 males – 26 females, aged 54 +/− 12 years) with carcinoid syndrome and 30 normal subjects (12 males – 18 females, aged 55 +/− 10 years) who served as the control group were electrocardiographically examined. Parameters measured included early and late atrioventricular flow velocities (E and A wave respectively), E/A ratio, deceleration time, and isovolumic relaxation time (IVRT= time from semilunar valve closure to atrioventricular valve opening). Results: See table. We found significant correlation between deceleration time and urinary levels of 5-HIAA (r= −0.34, p<0.05). There were no differences between the two groups regarding the heart rate or the left ventricular diastolic indices. Conclusions: Right ventricular diastolic function is impaired in patients with carcinoid syndrome without obvious carcinoid involvement. Right ventricular dysfunction could be the earliest sign of cardiac involvement, perhaps as a result of endomyocardial involvement of the disease.⇓