Blood Pressure Control in Hispanic Participants in the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
In contrast to Black non-Hispanics (BNH), Hispanic Americans have a prevalence of hypertension that is similar to the White non-Hispanic (WNH)population. However, compared to BNH and WNH, hypertension awareness, treatment and control are much lower in Hispanics. ALLHAT is a double-blind randomized controlled trial in high-risk hypertensives age >=55, comparing the effects of treatment with chlorthalidone, amlodipine, doxazosin and lisinopril (Step 1) on cardiovascular events. Open label treatment with atenolol, clonidine, reserpine (Step 2), and hydralazine (Step 3) may be added as necessary to achieve the goal of <140 systolic (SBP) and <90 diastolic (DBP). There are 32,398 participants with follow-up data at 24 months. Both White and Black Hispanics had similar SBP and BP control to WNH at 24 months of followup. Fewer Hispanics were taking maximal dose Step 1 or Step 2/3 medications. These results suggest that equal access to care can lead to equal BP control in White non-Hispanic and Hispanic Americans.⇓