Postural Hypotension Induced by Atropine Sulfate
Previous tests on the use of large doses of atropine for the treatment of anticholinesterase poisoning have revealed postural hypotension following the administration of 2 mg. of this drug. In this study on 78 normal adult males, the cardiovascular responses to positional change after 2 mg. atropine have been measured and the mechanisms elucidated. Blood pressure response to tilting was normal during control and placebo phases, but showed a profound alteration after atropine.
- © 1954 American Heart Association, Inc.