Donate Help Contact The AHA Sign In Home
American Heart Association
Circulation
Search: search_blue_button Advanced Search
Published Online
on March 9, 2009

Circulation. 2009
Published online before print March 9, 2009, doi: 10.1161/CIRCULATIONAHA.108.805135
A more recent version of this article appeared on March 24, 2009
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
119/11/1467    most recent
CIRCULATIONAHA.108.805135v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Scherptong, R. W.C.
Right arrow Articles by Hazekamp, M. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Scherptong, R. W.C.
Right arrow Articles by Hazekamp, M. G.
Related Collections
Right arrow Contractile function
Right arrow Other heart failure
Right arrow Echocardiography
Right arrow Pediatric and congenital heart disease, including cardiovascular surgery
Right arrowRelated Article

Submitted on July 7, 2008
Accepted on January 16, 2009

Tricuspid Valve Surgery in Adults With a Dysfunctional Systemic Right Ventricle. Repair or Replace?

Roderick W.C. Scherptong MD, Hubert W. Vliegen MD, PhD*, Michiel M. Winter MD, Eduard R. Holman MD, PhD, Barbara J.M. Mulder MD, PhD, Ernst E. van der Wall MD, PhD, and Mark G. Hazekamp MD, PhD

From the Department of Cardiology, Leiden University Medical Center (R.W.C.S., H.W.V., E.R.H., E.E.v.d.W.), Leiden, the Netherlands; Department of Cardiology, Amsterdam Medical Center (M.M.W., B.J.M.M.), Amsterdam, the Netherlands; Department of Cardiology, University Medical Center Utrecht (B.J.M.M.), Utrecht, the Netherlands; and Department of Cardiothoracic Surgery, Leiden University Medical Center and Amsterdam Medical Center (M.G.H.).

* To whom correspondence should be addressed. E-mail: H.W.Vliegen{at}lumc.nl.

Background—In patients with a right ventricle (RV) in the systemic position, tricuspid valve surgery for regurgitation beyond adolescence is a subject of debate. The aim of the present study was to evaluate the complications, survival, and benefit of tricuspid surgery in adult patients with an atrium-level correction for transposition of the great arteries or congenitally corrected transposition of the great arteries.

Methods and Results—All adult patients (n=16; 7 men, 9 women; age 35±11 years) who underwent tricuspid valvuloplasty (n=8) or replacement (n=8) in the period 1999 to 2008 were included. Complications and survival were analyzed, and postoperative changes in RV function and functional class were evaluated. Tricuspid regurgitation was graded 1 to 4 according to its severity, RV dysfunction was graded as 1 to 4 (1=no dysfunction to 4=severe dysfunction), and functional status was determined according to New York Heart Association class. Although complications occurred in 11 patients, all could be managed adequately. Three patients died 109, 180, and 659 days after surgery, respectively, the first patient after tricuspid valve replacement and the latter 2 after tricuspid valvuloplasty. Overall, tricuspid valve function improved (from grade 3.1±0.8 to 0.9±1.0; P=0.001) and functional class improved (from 2.7±0.6 to 2.1±0.8; P=0.007), whereas RV function remained unchanged. After tricuspid valvuloplasty, however, recurrent moderate tricuspid valve regurgitation was observed frequently (n=3; 37%).

Conclusions—Mortality is rather low after tricuspid surgery in adult patients with mild to moderate RV dysfunction. In general, tricuspid valve function and functional class improve significantly after surgery, and systemic RV function is preserved. Tricuspid valvuloplasty, however, is associated with a high rate of recurrence of regurgitation.


Key words: heart defects, congenital • transposition of great vessels • valves • surgery • valvuloplasty • survival


Related Article:

Clinical Summaries
Circulation 2009 119: 1457-1458. [Extract] [Full Text]