Donate Help Contact The AHA Sign In Home
American Heart Association
Circulation
Search: search_blue_button Advanced Search
Published Online
on February 19, 2008

Circulation. 2008
Published online before print February 19, 2008, doi: 10.1161/CIRCULATIONAHA.107.687764
A more recent version of this article appeared on March 4, 2008
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
117/9/1201    most recent
CIRCULATIONAHA.107.687764v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Fratz, S.
Right arrow Articles by Hess, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fratz, S.
Right arrow Articles by Hess, J.
Related Collections
Right arrow Other Treatment
Right arrow Pediatric and congenital heart disease, including cardiovascular surgery
Right arrowRelated Article

Submitted on January 4, 2007
Accepted on December 7, 2007

Aortic Valvuloplasty in Pediatric Patients Substantially Postpones the Need for Aortic Valve Surgery. A Single-Center Experience of 188 Patients After up to 17.5 Years of Follow-Up

Sohrab Fratz MD*, Hans Peter Gildein MD, Gunter Balling MD, Walter Sebening MD, Thomas Genz MD, Andreas Eicken MD, and John Hess MD

From the Department of Pediatric Cardiology and Congenital Heart Disease, Deutsches Herzzentrum München, Klinik an der Technischen Universität München, Munich, Germany.

* To whom correspondence should be addressed. E-mail: fratz{at}dhm.mhn.de.

Background—Aortic valvuloplasty (AoVP) is an established procedure regarded as a valid alternative for surgical management of congenital aortic valve stenosis. However, its long-term efficacy in preventing or postponing aortic valve surgery remains uncertain for the individual patient. Therefore, the aim of this study was to study the long-term results of AoVP in pediatric patients and its efficacy in preventing or postponing aortic valve surgery.

Methods and Results—We reviewed up to 17.5 years of follow-up data of all 188 patients who received AoVP at the Deutsches Herzzentrum München. The patients were divided into those <1 month of age (group <1 month; n=68) and those ≥1 month of age (group ≥1 month; n=120) at the time of AoVP. After the first and second AoVP, moderate and severe aortic regurgitation developed in 29% and 14%, respectively, of the patients in group <1 month and in 19% and 29%, respectively, of the patients in group ≥1 month. Survival after 10 years free from aortic valve surgery was 59% (95% confidence interval, 45 to 73) in group <1 month and 70% (95% confidence interval, 59 to 81) in group ≥1 month.

Conclusions—This study shows that the long-term results of AoVP of congenital aortic valve stenosis in pediatric patients and its efficacy in preventing or postponing aortic valve surgery are very good. About two thirds of the patients are free from aortic valve surgery 10 years after AoVP.


Key words: aortic valve stenosis • balloon • catheterization • pediatrics • valvuloplasty


Related Article:

Clinical Summaries
Circulation 2008 117: 1121-1123. [Extract] [Full Text]



This article has been cited by other articles:


Home page
ESC Textbook of Cardiovascular MedicineHome page
J. E. Deanfield, R. Yates, F. J. Meijboom, and B. J.M. Mulder
CHAPTER 10 Congenital Heart Disease in Children and Adults
ESC Textbook of Cardiovascular Medicine, January 1, 2009; 2(1): med-9780199566990-chapter - med-9780199566990-chapter.
[Abstract] [Full Text] [PDF]