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Circulation. 1998;98:383-384

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(Circulation. 1998;98:383-384.)
© 1998 American Heart Association, Inc.


Cardiovascular News

Two Sides of the Same Coin

Stop Angiogenesis for Cancer and Encourage It for Coronary Artery Disease

Ruth SoRelle, Circulation Newswriter

A headline in the New York Times unexpectedly pushed the work of Judah Folkman, MD, into the limelight recently, making his >30 years of research into angiogenesis seem like an overnight success. It is a position that puts Folkman ill at ease. He is not comfortable with hyperbole about the research he has conducted at Boston's Children's Hospital and Harvard University Medical Center.

The New York Times front-page story drew a storm of enthusiasm and then skepticism. Folkman appeared bemused by the flurry of interest. He has been working quietly in the field of angiogenesis for so long that he had not anticipated the hubbub that the story caused. And he was not ready to have much known about his study until it had been proven in thousands of patients. Judah Folkman is the first to say that he can cure cancer—in mice.

Others are more generous in their praise. James Willerson, MD, editor of Circulation, medical director at the Texas Heart Institute, and chairman of the department of medicine at the University of Texas Medical School at Houston, called him "the father of angiogenesis." Folkman gave the annual Willerson Lecture at the University of Texas Health Science Center at Houston. Dr Isaiah Fidler, chairman of the department of cell biology at the University of Texas M.D. Anderson Cancer Center, is an admiring collaborator of Folkman's. "He is a beacon of hope. He is a national treasure. He is intuitive, brilliant, and unafraid of the unknown. He persisted, and . . . [Full Text of this Article]




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