This Article Full Text Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Ozaki, Y. Articles by Serruys, P. W. Search for Related Content PubMed PubMed Citation Articles by Ozaki, Y. Articles by Serruys, P. W.

(Circulation. 1997;96:491-499.)
© 1997 American Heart Association, Inc.

Articles

Comparison of Coronary Luminal Quantification Obtained From Intracoronary Ultrasound and Both Geometric and Videodensitometric Quantitative Angiography Before and After Balloon Angioplasty and Directional Atherectomy

Yukio Ozaki, MD, PhD; Andonis G. Violaris, MB, MD, MRCP; Tadashi Kobayashi, MD, PhD; David Keane, MB, PhD, MRCPI; Edoardo Camenzind, MD; Carlo Di Mario, MD, PhD; Pim de Feyter, MD, PhD; Jos R. T. C. Roelandt, MD, PhD; ; Patrick W. Serruys, MD, PhD

From the Angiographic Research Laboratory, Thoraxcenter, Erasmus University, Rotterdam, Netherlands, and the Division of Cardiology (Y.O., T.K.), Third Department of Internal Medicine, Aichi Medical University, Nagakute, Aichi, Japan.

Correspondence to Patrick W. Serruys, MD, PhD, FESC, FACC, Professor of Interventional Cardiology, Thoraxcenter, Erasmus University, PO Box 1738, 3000 DR Rotterdam, Netherlands.

Background Debate exists regarding the relationship between angiographic and intracoronary ultrasound (ICUS) measurements of minimal luminal cross-sectional area after coronary intervention. We investigated this and the factors that may influence it by using ICUS and quantitative angiography.

Methods and Results Patients who underwent successful balloon angioplasty (n=100) or directional atherectomy (n=50) were examined by using ICUS and quantitative angiography (edge-detection [ED] and videodensitometry [VID]) before and after intervention. Luminal damage postintervention was qualitatively graded into three categories based on angiographic results (smooth lumen, haziness, or dissection). Correlation of minimal luminal cross-sectional area measurements by ICUS and ED was .59 before and .47 after balloon angioplasty. Correlation between ICUS and VID was .50 before and .63 after balloon angioplasty. Postintervention, the difference between ICUS and VID was less than the difference between ICUS and ED (P<.01). Additionally, the correlation was .74 between ICUS and ED measurements and .78 between ICUS and VID measurements in the smooth lumen group, .46 and .63, respectively, in the presence of haziness, and .26 and .46, respectively, in lesions with dissection. Similar results were obtained after directional atherectomy: the agreement between ICUS and quantitative angiography deteriorated according to the degree of vessel damage, but less so with VID than ED.

Conclusions Complex morphological changes induced by intervention may contribute to discordance between the two quantitative imaging techniques. In the absence of ICUS, VID may be a complementary technique to ED in lesions with complex morphology after balloon angioplasty and directional atherectomy.

Key Words: angiography • angioplasty • imaging • coronary disease • ultrasonics

This article has been cited by other articles:

				F. Alfonso Nonocclusive coronary dissections: to stent or not to stent? J. Am. Coll. Cardiol., July 1, 2000; 36(1): 303 - 304. [Full Text] [PDF]

				F. Alfonso Videodensitometric vs edge-detection quantitative angiography. Insights from intravascular ultrasound imaging Eur. Heart J., April 2, 2000; 21(8): 604 - 607. [PDF]

				R.J.G Peters, W.E.M Kok, G Pasterkamp, C Von Birgelen, M Prins, and P.W Serruys Videodensitometric quantitative angiography after coronary balloon angioplasty, compared to edge-detection quantitative angiography and intracoronary ultrasound imaging Eur. Heart J., April 2, 2000; 21(8): 654 - 661. [Abstract] [PDF]

				P. W. Serruys, I. P. Kay, C. Disco, N. V. Deshpande, P. J. de Feyter, and on behalf of the BENESTENT I BENESTENT II Pilot BE Periprocedural quantitative coronary angiography after Palmaz-Schatz stent implantation predicts the restenosis rate at six months: Results of a meta-analysis of the belgian netherlands stent study (BENESTENT) I, BENESTENT II pilot, BENESTENT II and MUSIC trials J. Am. Coll. Cardiol., October 1, 1999; 34(4): 1067 - 1074. [Abstract] [Full Text] [PDF]