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Circulation. 1995;92:1151-1158

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(Circulation. 1995;92:1151-1158.)
© 1995 American Heart Association, Inc.


Articles

Magnetic Resonance Imaging Assessment of the Severity of Mitral Regurgitation

Comparison With Invasive Techniques

W. Gregory Hundley, MD; Hong F. Li, BS; John E. Willard, MD; Charles Landau, MD; Richard A. Lange, MD; Benjamin M. Meshack; L. David Hillis, MD; Ronald M. Peshock, MD

From the Departments of Internal Medicine, Cardiovascular Division (W.G.H., J.E.W., C.L., R.A.L., B.M.M., L.D.H., R.M.P.), and Radiology (H.F.L., R.M.P.), University of Texas Southwestern Medical Center, Dallas.

Correspondence to Ronald M. Peshock, MD, Mary Nell and Ralph B. Rogers Magnetic Resonance Center, University of Texas, Southwestern Medical Center, 5801 Forest Park, Dallas, TX 75235-9085. E-mail peshock@rad-rogers.swmed.edu.

Background In the patient with mitral regurgitation who is being considered for valvular surgery, cardiac catheterization is usually performed to quantify the severity of regurgitation and to determine its influence on left ventricular volumes and systolic function. Magnetic resonance imaging (MRI) potentially provides a rapid, noninvasive method of acquiring these data. Thus, this study was done to determine whether MRI can reliably measure the magnitude of mitral regurgitation and evaluate the effect of regurgitation on left ventricular volumes and systolic function.

Methods and Results Twenty-three subjects (14 women and 9 men 15 to 72 years of age) with (n=17) or without (n=6) mitral regurgitation underwent MRI scanning followed immediately by cardiac catheterization. The presence (or absence) of valvular regurgitation was determined, and left ventricular volumes and regurgitant fraction were quantified during each procedure. There was excellent correlation between invasive and MRI assessments of left ventricular end-diastolic (r=.95) and end-systolic (r=.95) volumes and regurgitant fraction (r=.96). All MRI examinations were completed in <28 minutes.

Conclusions In the patient with mitral regurgitation, MRI compares favorably with cardiac catheterization for assessment of the magnitude of regurgitation and its influence on left ventricular volumes and systolic function.


Key Words: regurgitation • magnetic resonance imaging • mitral valve • cardiovascular images • blood flow




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