Circulation, Vol 90, 2280-2284, Copyright © 1994 by American Heart Association
SG Ellis, ER da Silva, G Heyndrickx, JD Talley, C Cernigliaro, G Steg, C Spaulding, M Nobuyoshi, R Erbel and C Vassanelli
BACKGROUND--When used in the setting of acute myocardial infarction,
intravenous thrombolytic agents fail to achieve early infarct artery
patency in 15% to 50% of patients. We tested the hypothesis that immediate
balloon angioplasty applied to patients with failed early reperfusion would
improve left ventricular function and clinical outcome at 30 days compared
with conservative management alone. METHODS AND RESULTS--One hundred
fifty-one patients with first anterior wall infarction treated with any
accepted intravenous thrombolytic regimen and angiographically demonstrated
to have an occluded infarct vessel within 8 hours of chest pain onset were
randomized to aspirin, heparin, and coronary vasodilators (conservative
therapy) or to this therapy and balloon angioplasty supplemented by further
thrombolytic therapy as needed. Left ventricular function was assessed
using multiple-gated equilibrium radionuclide technique to determine
ejection fraction, and adverse clinical outcome was assessed evaluating
death, ventricular tachycardia, and class III or IV heart failure at 30
days. Seventy- three patients were randomized to conservative therapy and
78 to angioplasty. The two groups were well balanced for patient age (59
+/- 11 years), sex (82% were male), and time to randomization (4.5 +/- 1.9
hours). Angioplasty was technically successful in 72 of 78 randomized
patients (92%). Two patients randomized to conservative therapy crossed
over to angioplasty within 72 hours. Resting 30-day ejection fraction was
40 +/- 11% in the angioplasty group and 39 +/- 12% in the conservative
group (P = .49), but ejection fraction with exercise was 43 +/- 15% and 38
+/- 13% for the angioplasty and conservatively treated groups, respectively
(P = .04). Adverse clinical outcomes included death in 5% and 10% (P =
.18), severe heart failure in 1% and 7% (P = .11), and either death or
severe heart failure in 6% and 17% (P = .05) of the angioplasty and
conservatively managed groups, respectively. CONCLUSIONS--When applied to
patients with first anterior infarction, rescue angioplasty appears to be
useful in the prevention of death or severe heart failure, with improvement
in exercise, but not resting, ejection fraction. This strategy deserves
further study and highlights the potential advantage of early mechanical
restoration of infarct vessel patency when thrombolytic therapy has failed.
ARTICLES
Randomized comparison of rescue angioplasty with conservative management of patients with early failure of thrombolysis for acute anterior myocardial infarction
Cleveland Clinic Foundation, OH 44195.
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||||
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||||
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||||
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||||
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||||
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||||
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Tackling myocardial infarction DTB, March 1, 2000; 38(3): 17 - 22. [Abstract] [Full Text] [PDF] |
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||||
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||||
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A. Sutton, P. O Lim, and P. Shiels Treatment and prognosis after myocardial infarction BMJ, August 8, 1998; 317(7155): 417 - 417. [Full Text] |
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||||
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T. Laperche, P. G. Steg, M. Dehoux, J. Benessiano, G. Grollier, E. Aliot, J.-M. Mossard, P. Aubry, D. Coisne, M. Hanssen, et al. A Study of Biochemical Markers of Reperfusion Early After Thrombolysis for Acute Myocardial Infarction Circulation, October 15, 1995; 92(8): 2079 - 2086. [Abstract] [Full Text] |
||||
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||||
![]() |
RESCUE ANGIOPLASTY AFTER FAILED THROMBOLYSIS Journal Watch (General), November 22, 1994; 1994(1122): 4 - 4. [Full Text] |
||||
![]() |
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