Circulation, Vol 88, 2685-2692, Copyright © 1993 by American Heart Association
SE Sutherland, PC Gazes, JE Keil, GE Gilbert and RG Knapp
BACKGROUND. The long-term predictive significance of a single ECG tracing
for mortality was explored among the white and black men of the Charleston
Heart Study. METHODS AND RESULTS. The 1960 baseline tracings of men ages 35
to 74 in the Charleston Heart Study cohort were coded according to the
Minnesota classification. Tracings were categorized as being normal or
having minor or major abnormalities. The 30-year vital status was
ascertained for the cohort, and the association between ECG findings and
coronary and all-cause mortality was evaluated. The proportion of black men
with major abnormalities at the 1960 baseline examination was almost twice
that of white men. Rates of all-cause mortality increased with severity of
abnormalities for white and black men. The absolute excess risk for black
men with major abnormalities was 23.3 per 1000 person-years and 12.8 for
white men. The excess risk for coronary mortality was 7.3 for white men and
6.5 for black men. CONCLUSIONS. Many of the findings in this study confirm
earlier associations derived from studies of white populations and extend
the observations to black men. However, the magnitude of the relative risk
for mortality was different for white and black men. After controlling for
traditional coronary disease risk factors and minor abnormalities, white
men with major abnormalities were 2.72 (95% confidence interval, 1.47,
5.04) times more likely to die of coronary disease compared with black men,
who were 1.95 (95% confidence interval, 0.93, 4.11) times more likely to
die of coronary disease.
ARTICLES
Electrocardiographic abnormalities and 30-year mortality among white and black men of the Charleston Heart Study
Department of Biometry and Epidemiology, Medical University of South Carolina, Charleston 29425.
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