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Circulation. 1988;78:1157-1166

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Circulation, Vol 78, 1157-1166, Copyright © 1988 by American Heart Association


ARTICLES

Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease?

WC Little, M Constantinescu, RJ Applegate, MA Kutcher, MT Burrows, FR Kahl and WP Santamore
Department of Medicine, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27103.

To help determine if coronary angiography can predict the site of a future coronary occlusion that will produce a myocardial infarction, the coronary angiograms of 42 consecutive patients who had undergone coronary angiography both before and up to a month after suffering an acute myocardial infarction were evaluated. Twenty-nine patients had a newly occluded coronary artery. Twenty-five of these 29 patients had at least one artery with a greater than 50% stenosis on the initial angiogram. However, in 19 of 29 (66%) patients, the artery that subsequently occluded had less than a 50% stenosis on the first angiogram, and in 28 of 29 (97%), the stenosis was less than 70%. In every patient, at least some irregularity of the coronary wall was present on the first angiogram at the site of the subsequent coronary obstruction. In only 10 of the 29 (34%) did the infarction occur due to occlusion of the artery that previously contained the most severe stenosis. Furthermore, no correlation existed between the severity of the initial coronary stenosis and the time from the first catheterization until the infarction (r2 = 0.0005, p = NS). These data suggest that assessment of the angiographic severity of coronary stenosis may be inadequate to accurately predict the time or location of a subsequent coronary occlusion that will produce a myocardial infarction.


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HeartHome page
T Giesler, S Lamprecht, J-U Voigt, D Ropers, K Pohle, J Ludwig, F A Flachskampf, W G Daniel, and U Nixdorff
Long term follow up after deferral of revascularisation in patients with intermediate coronary stenoses and negative dobutamine stress echocardiography
Heart, December 1, 2002; 88(6): 645 - 646.
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Postgrad. Med. J.Home page
P J Sheridan and D C Crossman
Critical review of unstable angina and non-ST elevation myocardial infarction
Postgrad. Med. J., December 1, 2002; 78(926): 717 - 726.
[Abstract] [Full Text] [PDF]


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Eur Heart J SupplHome page
A. DeFranco
Understanding the pathophysiology of the arterial wall: which method should we choose? Intra-vascular ultrasound
Eur. Heart J. Suppl., September 1, 2002; 4(suppl_F): F29 - F40.
[Abstract] [PDF]


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Eur Heart J SupplHome page
V. Fuster, R. Corti, Z.A. Fayad, and J.J. Badimon
Understanding the pathophysiology of the arterial wall: which method should we choose? Magnetic resonance imaging
Eur. Heart J. Suppl., September 1, 2002; 4(suppl_F): F41 - F46.
[Abstract] [PDF]


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Cardiovasc ResHome page
K. K. Koh
Effects of estrogen on the vascular wall: vasomotor function and inflammation
Cardiovasc Res, September 1, 2002; 55(4): 714 - 726.
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CirculationHome page
T. J. Ryan
The Coronary Angiogram and Its Seminal Contributions to Cardiovascular Medicine Over Five Decades
Circulation, August 6, 2002; 106(6): 752 - 756.
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CirculationHome page
W. Y. Kim, M. Stuber, P. Bornert, K. V. Kissinger, W. J. Manning, and R. M. Botnar
Three-Dimensional Black-Blood Cardiac Magnetic Resonance Coronary Vessel Wall Imaging Detects Positive Arterial Remodeling in Patients With Nonsignificant Coronary Artery Disease
Circulation, July 16, 2002; 106(3): 296 - 299.
[Abstract] [Full Text] [PDF]


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Arterioscler. Thromb. Vasc. Bio.Home page
R. P. Choudhury, V. Fuster, J. J. Badimon, E. A. Fisher, and Z. A. Fayad
MRI and Characterization of Atherosclerotic Plaque: Emerging Applications and Molecular Imaging
Arterioscler Thromb Vasc Biol, July 1, 2002; 22(7): 1065 - 1074.
[Abstract] [Full Text] [PDF]


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CirculationHome page
P. R. Moreno, K. R. Purushothaman, V. Fuster, and W. N. O'Connor
Intimomedial Interface Damage and Adventitial Inflammation Is Increased Beneath Disrupted Atherosclerosis in the Aorta: Implications for Plaque Vulnerability
Circulation, May 28, 2002; 105(21): 2504 - 2511.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
R. A. Kerensky, M. Wade, P. Deedwania, W. E. Boden, C. J. Pepine, and Veterans Affairs Non-Q-Wave Infarction Strategies
Revisiting the culprit lesion in non-Q-wave myocardial infarction: Results from the VANQWISH trial angiographic core laboratory
J. Am. Coll. Cardiol., May 1, 2002; 39(9): 1456 - 1463.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
D. D. Miller
Coronary flow studies for risk stratification in multivessel disease: A physiologic bridge too far?
J. Am. Coll. Cardiol., March 6, 2002; 39(5): 859 - 863.
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Eur Heart JHome page
C. Di Mario
Vulnerable plaques: let's stop sinking on submerged icebergs?
Eur. Heart J., March 1, 2002; 23(5): 349 - 351.
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Eur Heart J SupplHome page
G.F. Gensini and B. Dilaghi
The unstable plaque
Eur. Heart J. Suppl., March 1, 2002; 4(suppl_B): B22 - B27.
[Abstract] [PDF]


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Eur Heart JHome page
E.G. Zouridakis, R. Schwartzman, X. Garcia-Moll, I.D. Cox, S. Fredericks, D.W. Holt, and J.C. Kaski
Increased plasma endothelin levels in angina patients with rapid coronary artery disease progression
Eur. Heart J., September 1, 2001; 22(17): 1578 - 1584.
[Abstract] [PDF]


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Arch Intern MedHome page
L. Schwartz and M. G. Bourassa
Evaluation of Patients With Chest Pain and Normal Coronary Angiograms
Arch Intern Med, August 13, 2001; 161(15): 1825 - 1833.
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CirculationHome page
P. C. Keelan, L. F. Bielak, K. Ashai, L. S. Jamjoum, A. E. Denktas, J. A. Rumberger, P. F. Sheedy, II, P. A. Peyser, and R. S. Schwartz
Long-Term Prognostic Value of Coronary Calcification Detected by Electron-Beam Computed Tomography in Patients Undergoing Coronary Angiography
Circulation, July 24, 2001; 104(4): 412 - 417.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
R. J. Krone, R. M. Hardison, B. R. Chaitman, R. J. Gibbons, G. Sopko, R. Bach, and K. M. Detre
Risk stratification after successful coronary revascularization: the lack of a role for routine exercise testing
J. Am. Coll. Cardiol., July 1, 2001; 38(1): 136 - 142.
[Abstract] [Full Text] [PDF]


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SEMIN CARDIOTHORAC VASC ANESTHHome page
D. A. Zvara
Treatment of Perioperative Myocardial Ischemia
Seminars in Cardiothoracic and Vascular Anesthesia, July 1, 2001; 5(2): 166 - 183.
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CirculationHome page
G. J. W. Bech, B. De Bruyne, N. H.J. Pijls, E. D. de Muinck, J. C.A. Hoorntje, J. Escaned, P. R. Stella, E. Boersma, J. Bartunek, J. J. Koolen, et al.
Fractional Flow Reserve to Determine the Appropriateness of Angioplasty in Moderate Coronary Stenosis : A Randomized Trial
Circulation, June 19, 2001; 103(24): 2928 - 2934.
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J Am Coll CardiolHome page
C. von Birgelen, W. Klinkhart, G. S. Mintz, A. Papatheodorou, J.o. Herrmann, D. Baumgart, M. Haude, H. Wieneke, J. Ge, and R. Erbel
Plaque distribution and vascular remodeling of ruptured and nonruptured coronary plaques in the same vessel: an intravascular ultrasound study in vivo
J. Am. Coll. Cardiol., June 1, 2001; 37(7): 1864 - 1870.
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J Am Coll CardiolHome page
F. Ledru, P. Ducimetiere, S. Battaglia, D. Courbon, F. Beverelli, L. Guize, J.-L.e. Guermonprez, and B. Diebold
New diagnostic criteria for diabetes and coronary artery disease: insights from an angiographic study
J. Am. Coll. Cardiol., May 1, 2001; 37(6): 1543 - 1550.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
I. Gradus-Pizlo, S. G. Sawada, D. Wright, D. S. Segar, and H. Feigenbaum
Detection of subclinical coronary atherosclerosis using two-dimensional, high-resolution transthoracic echocardiography
J. Am. Coll. Cardiol., April 1, 2001; 37(5): 1422 - 1429.
[Abstract] [Full Text] [PDF]