Circulation, Vol 70, 972-977, Copyright © 1984 by American Heart Association
B Olshansky, SM Collins, DJ Skorton and NV Prasad
Integrated ultrasonic backscatter from normal myocardium has been shown to
vary with the phase of cardiac contraction (decreasing from end- diastole
to end-systole) in previous studies of open-chest dogs. If confirmed, this
finding would have important implications for clinical application of
ultrasonic tissue characterization. Our hypothesis was that a cardiac
cycle-dependent variation in regional average gray level would be detected
on analysis of digitized two-dimensional echocardiograms. We analyzed
echocardiographic images from 16 subjects in whom normal, technically good
studies were obtained with a commercial phased-array scanner and a 2.25 MHz
transducer. Images from six subjects were digitized from stop-frame
photographs and those from 10 subjects were obtained directly in digital
format from the scanner. Average gray level was measured in a portion of
the left ventricular posterior wall in parasternal long-axis images
obtained at end-diastole and end-systole by both photographic and
digital-image acquisition. In seven of the subjects from whom digital
images were acquired, left ventricular posterior wall gray level and
ventricular septal gray level were also evaluated on parasternal short-axis
images. In images digitized by the photographic technique, mean posterior
wall gray level decreased significantly from end-diastole (175 +/- 5.8 SEM)
to end- systole (167 +/- 5.1, p less than .05). Similarly, in images
digitized directly, mean posterior wall gray level in the long-axis view
decreased from end-diastole (71 +/- 3.4) to end-systole (59 +/- 2.5, p less
than .005).(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
Variation of left ventricular myocardial gray level on two-dimensional echocardiograms as a result of cardiac contraction
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