Circulation, Vol 64, 744-753, Copyright © 1981 by American Heart Association
MA Quinones, AD Waggoner, LA Reduto, JG Nelson, JB Young, WL Winters Jr, LG Ribeiro and RR Miller
A new method to determine left ventricular (LV) ejection fraction (EF) with
wide-angle, two-dimensional echocardiography (2-D echo) has been developed
using the parasternal long-axis, apical four-chamber and apical long-axis
views. End-diastolic and end-systolic measurements of LV short axes at the
base and mid-LV cavity in the parasternal long- axis view and at the upper,
middle and lower thirds of the cavity in the apical views are made, from
which an averaged minor axis at end- diastolic and at end-systole is
calculated. Fractional shortening of the LV long axis (delta L) is
estimated from apical contraction. Satisfactory 2-D echoes were obtained in
55 of 58 nonselected patients (all three views in 32 patients, two views in
22 and one view in one); 42 of 55 patients had coronary artery disease. EF
by 2-D echo was compared with EF by gated cardiac blood pool imaging in all
patients (r = 0.927, SEE = 6.7%) and to EF by single-plane cineangiography
(angio) in 35 of 55 patients (r = 0.913, SEE = 7.4%). LV dyssynergy was
frequently present and involved the apex in 29 of 55 patients. Using angio
as the standard for evaluating wall motion at the apex, 2-D echo was 100%
sensitive and specific in detecting abnormal apical wall motion. We
conclude that EF can be determined accurately with 2-D echo in a large
group of patients with and without dyssynergy by a simple method that
eliminates the need for planimetry or computer assistance.
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A new, simplified and accurate method for determining ejection fraction with two-dimensional echocardiography
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C. Y.T. Hart, D. M. Meyer, H. D. Tazelaar, J. P. Grande, J. C. Burnett Jr, P. R. Housmans, and M. M. Redfield Load Versus Humoral Activation in the Genesis of Early Hypertensive Heart Disease Circulation, July 10, 2001; 104(2): 215 - 220. [Abstract] [Full Text] [PDF]
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T. Tabata, S. S. Kabbani, R. D. Murray, J. D. Thomas, I. Abdalla, and A. L. Klein Difference in the respiratory variation between pulmonary venous and mitral inflow doppler velocities in patients with constrictive pericarditis with and without atrial fibrillation J. Am. Coll. Cardiol., June 1, 2001; 37(7): 1936 - 1942. [Abstract] [Full Text] [PDF]
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S. F. Nagueh, S. J. Stetson, N. M. Lakkis, D. Killip, A. Perez-Verdia, M. L. Entman, W. H. Spencer III, and G. Torre-Amione Decreased Expression of Tumor Necrosis Factor-{{alpha}} and Regression of Hypertrophy After Nonsurgical Septal Reduction Therapy for Patients With Hypertrophic Obstructive Cardiomyopathy Circulation, April 10, 2001; 103(14): 1844 - 1850. [Abstract] [Full Text] [PDF]
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F. Grigioni, M. Enriquez-Sarano, K. J. Zehr, K. R. Bailey, and A. J. Tajik Ischemic Mitral Regurgitation : Long-Term Outcome and Prognostic Implications With Quantitative Doppler Assessment Circulation, April 3, 2001; 103(13): 1759 - 1764. [Abstract] [Full Text] [PDF]
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K. Shan, R. J. Bick, B. J. Poindexter, S. F. Nagueh, S. Shimoni, M. S. Verani, F. Keng, M. J. Reardon, G. V. Letsou, J. F. Howell, et al. Altered Adrenergic Receptor Density in Myocardial Hibernation in Humans : A Possible Mechanism of Depressed Myocardial Function Circulation, November 21, 2000; 102(21): 2599 - 2606. [Abstract] [Full Text] [PDF]
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C Bruch, A Schmermund, D Marin, M Katz, T Bartel, J Schaar, and R Erbel Tei-Index in patients with mild-to-moderate congestive heart failure Eur. Heart J., November 2, 2000; 21(22): 1888 - 1895. [Abstract] [PDF]
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A. J. Rainbird, P. A. Pellikka, V. L. Stussy, D. M. Mahoney, and J. B. Seward A rapid stress-testing protocol for the detection of coronary artery disease: Comparison of two-stage transesophageal atrial pacing stress echocardiography with dobutamine stress echocardiography J. Am. Coll. Cardiol., November 1, 2000; 36(5): 1659 - 1663. [Abstract] [Full Text] [PDF]
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M. K. Das, P. A. Pellikka, D. W. Mahoney, V. L. Roger, J. K. Oh, R. B. McCully, and J. B. Seward Assessment of cardiac risk before nonvascular surgery: Dobutamine stress echocardiography in 530 patients J. Am. Coll. Cardiol., May 1, 2000; 35(6): 1647 - 1653. [Abstract] [Full Text] [PDF]
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H. M. Connolly, J. K. Oh, H. V. Schaff, V. L. Roger, S. L. Osborn, D. O. Hodge, and A. J. Tajik Severe Aortic Stenosis With Low Transvalvular Gradient and Severe Left Ventricular Dysfunction : Result of Aortic Valve Replacement in 52 Patients Circulation, April 25, 2000; 101(16): 1940 - 1946. [Abstract] [Full Text] [PDF]
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J. M. Cwajg, E. Cwajg, S. F. Nagueh, Z.-X. He, U. Qureshi, L. I. Olmos, M. A. Quinones, M. S. Verani, W. L. Winters, and W. A. Zoghbi End-diastolic wall thickness as a predictor of recovery of function in myocardial hibernation: Relation to rest-redistribution Tl-201 tomography and dobutamine stress echocardiography J. Am. Coll. Cardiol., April 1, 2000; 35(5): 1152 - 1161. [Abstract] [Full Text] [PDF]
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M. A. Quinones, B. H. Greenberg, H. A. Kopelen, C. Koilpillai, M. C. Limacher, D. M. Shindler, B. J. Shelton, D. H. Weiner, and for the SOLVD Investigators Echocardiographic predictors of clinical outcome in patients with left ventricular dysfunction enrolled in the SOLVD registry and trials: significance of left ventricular hypertrophy J. Am. Coll. Cardiol., April 1, 2000; 35(5): 1237 - 1244. [Abstract] [Full Text] [PDF]
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D. L. Milavetz, S. N. Hayes, S. A. Weston, J. B. Seward, C. J. Mullany, and V. L. Roger Sex Differences in Left Ventricular Geometry in Aortic Stenosis: Impact on Outcome Chest, April 1, 2000; 117(4): 1094 - 1099. [Abstract] [Full Text] [PDF]
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O. W. Nielsen, J. F. Hansen, J. Hilden, C. T. Larsen, and J. Svanegaard Risk assessment of left ventricular systolic dysfunction in primary care: cross sectional study evaluating a range of diagnostic tests BMJ, January 22, 2000; 320(7229): 220 - 224. [Abstract] [Full Text]
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A. Colao, R. Baldelli, P. Marzullo, E. Ferretti, D. Ferone, P. Gargiulo, M. Petretta, G. Tamburrano, G. Lombardi, and A. Liuzzi Systemic Hypertension and Impaired Glucose Tolerance Are Independently Correlated to the Severity of the Acromegalic Cardiomyopathy J. Clin. Endocrinol. Metab., January 1, 2000; 85(1): 193 - 199. [Abstract] [Full Text]
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F. Grigioni, M. Enriquez-Sarano, L. H. Ling, K. R. Bailey, J. B. Seward, A. J. Tajik, and R. L. Frye Sudden death in mitral regurgitation due to flail leaflet J. Am. Coll. Cardiol., December 1, 1999; 34(7): 2078 - 2085. [Abstract] [Full Text] [PDF]
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S. F. Nagueh, I. Mikati, D. Weilbaecher, M. J. Reardon, G. J. Al-Zaghrini, D. Cacela, Z.-X. He, G. Letsou, G. Noon, J. F. Howell, et al. Relation of the Contractile Reserve of Hibernating Myocardium to Myocardial Structure in Humans Circulation, August 3, 1999; 100(5): 490 - 496. [Abstract] [Full Text] [PDF]
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M. Senni, M. M. Redfield, L. H. Ling, G. K. Danielson, A. J. Tajik, and J. K. Oh Left ventricular systolic and diastolic function after pericardiectomy in patients with constrictive pericarditis: Doppler echocardiographic findings and correlation with clinical status J. Am. Coll. Cardiol., April 1, 1999; 33(5): 1182 - 1188. [Abstract] [Full Text] [PDF]
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A. Mesa, C. Jessurun, A. Hernandez, K. Adam, D. Brown, W. K. Vaughn, and S. Wilansky Left Ventricular Diastolic Function in Normal Human Pregnancy Circulation, February 2, 1999; 99(4): 511 - 517. [Abstract] [Full Text] [PDF]
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L. I. Olmos, H. Dakik, R. Gordon, J. K. Dunn, M. S. Verani, M. A. Quinones, and W. A. Zoghbi Long-Term Prognostic Value of Exercise Echocardiography Compared With Exercise 201Tl, ECG, and Clinical Variables in Patients Evaluated for Coronary Artery Disease Circulation, December 15, 1998; 98(24): 2679 - 2686. [Abstract] [Full Text] [PDF]
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J. Barbetseas, S. F. Nagueh, C. Pitsavos, P. K. Toutouzas, M. A. Quinones, and W. A. Zoghbi Differentiating thrombus from pannus formation in obstructed mechanical prosthetic valves: an evaluation of clinical, transthoracic and transesophageal echocardiographic parameters J. Am. Coll. Cardiol., November 1, 1998; 32(5): 1410 - 1417. [Abstract] [Full Text] [PDF]
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N. M. Lakkis, S. F. Nagueh, N. S. Kleiman, D. Killip, Z.-X. He, M. S. Verani, R. Roberts, and W. H. Spencer III Echocardiography-Guided Ethanol Septal Reduction for Hypertrophic Obstructive Cardiomyopathy Circulation, October 27, 1998; 98(17): 1750 - 1755. [Abstract] [Full Text] [PDF]
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S. F. Nagueh, I. Mikati, H. A. Kopelen, K. J. Middleton, M. A. Quinones, and W. A. Zoghbi Doppler Estimation of Left Ventricular Filling Pressure in Sinus Tachycardia : A New Application of Tissue Doppler Imaging Circulation, October 20, 1998; 98(16): 1644 - 1650. [Abstract] [Full Text] [PDF]
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S.-C. Chuah, P. A. Pellikka, V. L. Roger, R. B. McCully, and J. B. Seward Role of Dobutamine Stress Echocardiography in Predicting Outcome in 860 Patients With Known or Suspected Coronary Artery Disease Circulation, April 21, 1998; 97(15): 1474 - 1480. [Abstract] [Full Text] [PDF]
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L. H. Ling, M. Enriquez-Sarano, J. B. Seward, T. A. Orszulak, H. V. Schaff, K. R. Bailey, A. J. Tajik, and R. L. Frye Early Surgery in Patients With Mitral Regurgitation Due to Flail Leaflets : A Long-term Outcome Study Circulation, September 16, 1997; 96(6): 1819 - 1825. [Abstract] [Full Text]
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H. M. Connolly, J. K. Oh, T. A. Orszulak, S. L. Osborn, V. L. Roger, D. O. Hodge, K. R. Bailey, J. B. Seward, and A. J. Tajik Aortic Valve Replacement for Aortic Stenosis With Severe Left Ventricular Dysfunction: Prognostic Indicators Circulation, May 20, 1997; 95(10): 2395 - 2400. [Abstract] [Full Text]
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M. D. Cheitlin, J. S. Alpert, W. F. Armstrong, G. P. Aurigemma, G. A. Beller, F. Z. Bierman, T. W. Davidson, J. L. Davis, P. S. Douglas, L. D. Gillam, et al. ACC/AHA Guidelines for the Clinical Application of Echocardiography : A Report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines (Committee on Clinical Application of Echocardiography) Developed in Collaboration With the American Society of Echocardiography Circulation, March 18, 1997; 95(6): 1686 - 1744. [Full Text]
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