Circulation, Vol 64, 744-753, Copyright © 1981 by American Heart Association
MA Quinones, AD Waggoner, LA Reduto, JG Nelson, JB Young, WL Winters Jr, LG Ribeiro and RR Miller
A new method to determine left ventricular (LV) ejection fraction (EF) with
wide-angle, two-dimensional echocardiography (2-D echo) has been developed
using the parasternal long-axis, apical four-chamber and apical long-axis
views. End-diastolic and end-systolic measurements of LV short axes at the
base and mid-LV cavity in the parasternal long- axis view and at the upper,
middle and lower thirds of the cavity in the apical views are made, from
which an averaged minor axis at end- diastolic and at end-systole is
calculated. Fractional shortening of the LV long axis (delta L) is
estimated from apical contraction. Satisfactory 2-D echoes were obtained in
55 of 58 nonselected patients (all three views in 32 patients, two views in
22 and one view in one); 42 of 55 patients had coronary artery disease. EF
by 2-D echo was compared with EF by gated cardiac blood pool imaging in all
patients (r = 0.927, SEE = 6.7%) and to EF by single-plane cineangiography
(angio) in 35 of 55 patients (r = 0.913, SEE = 7.4%). LV dyssynergy was
frequently present and involved the apex in 29 of 55 patients. Using angio
as the standard for evaluating wall motion at the apex, 2-D echo was 100%
sensitive and specific in detecting abnormal apical wall motion. We
conclude that EF can be determined accurately with 2-D echo in a large
group of patients with and without dyssynergy by a simple method that
eliminates the need for planimetry or computer assistance.
ARTICLES
A new, simplified and accurate method for determining ejection fraction with two-dimensional echocardiography
This article has been cited by other articles:
![]() |
T. Kara, M. Novak, J. Nykodym, K. A. Bybee, J. Meluzin, M. Orban, Z. Novakova, J. Lipoldova, D. L. Hayes, M. Soucek, et al. Short-term Effects of Cardiac Resynchronization Therapy on Sleep-Disordered Breathing in Patients With Systolic Heart Failure Chest, July 1, 2008; 134(1): 87 - 93. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. I. Michelena, V. A. Desjardins, J.-F. Avierinos, A. Russo, V. T. Nkomo, T. M. Sundt, P. A. Pellikka, A. J. Tajik, and M. Enriquez-Sarano Natural History of Asymptomatic Patients With Normally Functioning or Minimally Dysfunctional Bicuspid Aortic Valve in the Community Circulation, May 27, 2008; 117(21): 2776 - 2784. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. David, P. Kumpers, V. Seidler, F. Biertz, H. Haller, and D. Fliser Diagnostic value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) for left ventricular dysfunction in patients with chronic kidney disease stage 5 on haemodialysis Nephrol. Dial. Transplant., April 1, 2008; 23(4): 1370 - 1377. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Park, J.-W. Ha, C. Y. Shim, E.-Y. Choi, J.-M. Kim, J.-A. Ahn, S.-W. Lee, S.-J. Rim, and N. Chung Gender-Related Difference in Arterial Elastance During Exercise in Patients With Hypertension Hypertension, April 1, 2008; 51(4): 1163 - 1169. [Abstract] [Full Text] [PDF] |
||||
![]() |
S-W Lee, M-C Park, Y-B Park, and S-K Lee E/E' ratio is more sensitive than E/A ratio for detection of left ventricular diastolic dysfunction in systemic lupus erythematosus Lupus, March 1, 2008; 17(3): 195 - 201. [Abstract] [PDF] |
||||
![]() |
J.-W. Ha, H.-C. Lee, E.-S. Kang, C.-M. Ahn, J.-M. Kim, J.-A. Ahn, S.-W. Lee, E.-Y. Choi, S.-J. Rim, J. K Oh, et al. Abnormal left ventricular longitudinal functional reserve in patients with diabetes mellitus: implication for detecting subclinical myocardial dysfunction using exercise tissue Doppler echocardiography Heart, December 1, 2007; 93(12): 1571 - 1576. [Abstract] [Full Text] [PDF] |
||||
![]() |
O. Celik, I. Sahin, N. Celik, S. Hascalik, L. Keskin, H. Ozcan, A. Uckan, and F. Kosar Diagnostic potential of serum N-terminal pro-B-type brain natriuretic peptide level in detection of cardiac wall stress in women with polycystic ovary syndrome: a cross-sectional comparison study Hum. Reprod., November 1, 2007; 22(11): 2992 - 2998. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Bursi, S. A. Weston, M. M. Redfield, S. J. Jacobsen, S. Pakhomov, V. T. Nkomo, R. A. Meverden, and V. L. Roger Systolic and diastolic heart failure in the community. JAMA, November 8, 2006; 296(18): 2209 - 2216. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. P. Hudson, P. W. Armstrong, W. Ruzyllo, J. Brum, L. Cusmano, P. Krzeski, R. Lyon, M. Quinones, P. Theroux, D. Sydlowski, et al. Effects of Selective Matrix Metalloproteinase Inhibitor (PG-116800) to Prevent Ventricular Remodeling After Myocardial Infarction: Results of the PREMIER (Prevention of Myocardial Infarction Early Remodeling) Trial J. Am. Coll. Cardiol., July 4, 2006; 48(1): 15 - 20. [Abstract] [Full Text] [PDF] |
||||
![]() |
M D Thomas, K F Fox, D A Wood, J S R Gibbs, A J S Coats, M Y Henein, P A Poole-Wilson, and G C Sutton Echocardiographic features and brain natriuretic peptides in patients presenting with heart failure and preserved systolic function Heart, May 1, 2006; 92(5): 603 - 608. [Abstract] [Full Text] [PDF] |
||||
![]() |
M Weber, T Dill, A Deetjen, T Neumann, O Ekinci, J Hansel, A Elsaesser, V Mitrovic, and C Hamm Left ventricular adaptation after atrial septal defect closure assessed by increased concentrations of N-terminal pro-brain natriuretic peptide and cardiac magnetic resonance imaging in adult patients Heart, May 1, 2006; 92(5): 671 - 675. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Chaowalit, A. L. Arruda, R. B. McCully, K. R. Bailey, and P. A. Pellikka Dobutamine Stress Echocardiography in Patients With Diabetes Mellitus: Enhanced Prognostic Prediction Using a Simple Risk Score J. Am. Coll. Cardiol., March 7, 2006; 47(5): 1029 - 1036. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. M. Lang, M. Bierig, R. B. Devereux, F. A. Flachskampf, E. Foster, P. A. Pellikka, M. H. Picard, M. J. Roman, J. Seward, J. Shanewise, et al. Recommendations for chamber quantification Eur J Echocardiogr, March 1, 2006; 7(2): 79 - 108. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Alonso-Fernandez, F. Garcia-Rio, M. A. Arias, O. Mediano, J. M. Pino, I. Martinez, and J. Villamor Obstructive sleep apnoea-hypoapnoea syndrome reversibly depresses cardiac response to exercise Eur. Heart J., January 2, 2006; 27(2): 207 - 215. [Abstract] [Full Text] [PDF] |
||||
![]() |
J.-W. Ha, J.-A. Ahn, J.-Y. Moon, H.-S. Suh, S.-M. Kang, S.-J. Rim, Y. Jang, N. Chung, W.-H. Shim, and S.-Y. Cho Triphasic mitral inflow velocity with mid-diastolic flow: The presence of mid-diastolic mitral annular velocity indicates advanced diastolic dysfunction Eur J Echocardiogr, January 1, 2006; 7(1): 16 - 21. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. H Rutten, K. G M Moons, M.-J. M Cramer, D. E Grobbee, N. P A Zuithoff, J.-W. J Lammers, and A. W Hoes Recognising heart failure in elderly patients with stable chronic obstructive pulmonary disease in primary care: cross sectional diagnostic study BMJ, December 10, 2005; 331(7529): 1379. [Abstract] [Full Text] [PDF] |
||||
![]() |
J.-W. Ha, J.-R. Cho, J.-M. Kim, J.-A. Ahn, E.-Y. Choi, S.-M. Kang, S.-J. Rim, and N. Chung Tissue Doppler-Derived Indices Predict Exercise Capacity in Patients With Apical Hypertrophic Cardiomyopathy Chest, November 1, 2005; 128(5): 3428 - 3433. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. H. Rutten, M.-J. M. Cramer, D. E. Grobbee, A. P.E. Sachs, J. H. Kirkels, J.-W. J. Lammers, and A. W. Hoes Unrecognized heart failure in elderly patients with stable chronic obstructive pulmonary disease Eur. Heart J., September 2, 2005; 26(18): 1887 - 1894. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Briand, J. G. Dumesnil, L. Kadem, A. G. Tongue, R. Rieu, D. Garcia, and P. Pibarot Reduced Systemic Arterial Compliance Impacts Significantly on Left Ventricular Afterload and Function in Aortic Stenosis: Implications for Diagnosis and Treatment J. Am. Coll. Cardiol., July 19, 2005; 46(2): 291 - 298. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. A. Arias, F. Garcia-Rio, A. Alonso-Fernandez, O. Mediano, I. Martinez, and J. Villamor Obstructive Sleep Apnea Syndrome Affects Left Ventricular Diastolic Function: Effects of Nasal Continuous Positive Airway Pressure in Men Circulation, July 19, 2005; 112(3): 375 - 383. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. A. Pellikka, M. E. Sarano, R. A. Nishimura, J. F. Malouf, K. R. Bailey, C. G. Scott, M. E. Barnes, and A. J. Tajik Outcome of 622 Adults With Asymptomatic, Hemodynamically Significant Aortic Stenosis During Prolonged Follow-Up Circulation, June 21, 2005; 111(24): 3290 - 3295. [Abstract] [Full Text] [PDF] |
||||
![]() |
O. W. Nielsen, A. Sajedieh, F. Petersen, and J. Fischer Hansen Value of left ventricular filling parameters to predict mortality and functional class in patients with heart disease from the community Eur J Echocardiogr, March 1, 2005; 6(2): 85 - 91. [Abstract] [Full Text] [PDF] |
||||
![]() |
O. Salehian, E. Horlick, M. Schwerzmann, K. Haberer, P. McLaughlin, S. C. Siu, G. Webb, and J. Therrien Improvements in cardiac form and function after transcatheter closure of secundum atrial septal defects J. Am. Coll. Cardiol., February 15, 2005; 45(4): 499 - 504. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Bursi, M. Enriquez-Sarano, V. T. Nkomo, S. J. Jacobsen, S. A. Weston, R. A. Meverden, and V. L. Roger Heart Failure and Death After Myocardial Infarction in the Community: The Emerging Role of Mitral Regurgitation Circulation, January 25, 2005; 111(3): 295 - 301. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. J. Grande-Allen, A. G. Borowski, R. W. Troughton, P. L. Houghtaling, N. R. DiPaola, C. S. Moravec, I. Vesely, and B. P. Griffin Apparently normal mitral valves in patients with heart failure demonstrate biochemical and structural derangements: An extracellular matrix and echocardiographic study J. Am. Coll. Cardiol., January 4, 2005; 45(1): 54 - 61. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. J. Kernis, V. T. Nkomo, D. Messika-Zeitoun, B. J. Gersh, T. M. Sundt III, K. V. Ballman, C. G. Scott, H. V. Schaff, and M. Enriquez-Sarano Atrial Fibrillation After Surgical Correction of Mitral Regurgitation in Sinus Rhythm: Incidence, Outcome, and Determinants Circulation, October 19, 2004; 110(16): 2320 - 2325. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Orio Jr., S. Palomba, L. Spinelli, T. Cascella, L. Tauchmanova, F. Zullo, G. Lombardi, and A. Colao The Cardiovascular Risk of Young Women with Polycystic Ovary Syndrome: An Observational, Analytical, Prospective Case-Control Study J. Clin. Endocrinol. Metab., August 1, 2004; 89(8): 3696 - 3701. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Dokainish, W. A. Zoghbi, N. M. Lakkis, F. Al-Bakshy, M. Dhir, M. A. Quinones, and S. F. Nagueh Optimal Noninvasive Assessment of Left Ventricular Filling Pressures: A Comparison of Tissue Doppler Echocardiography and B-Type Natriuretic Peptide in Patients With Pulmonary Artery Catheters Circulation, May 25, 2004; 109(20): 2432 - 2439. [Abstract] [Full Text] [PDF] |
||||
![]() |
I. Ikonomidis, J. Lekakis, K. Stamatelopoulos, N. Markomihelakis, P. G. Kaklamanis, and M. Mavrikakis Aortic elastic properties and left ventricular diastolic function in patients with Adamantiades-Behcet's disease J. Am. Coll. Cardiol., March 17, 2004; 43(6): 1075 - 1081. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Yamaguchi, J. Yoshida, K. Yamamoto, Y. Sakata, T. Mano, N. Akehi, M. Hori, Y.-J. Lim, M. Mishima, and T. Masuyama Elevation of plasma brain natriuretic peptide is a hallmark of diastolic heart failure independent of ventricular hypertrophy J. Am. Coll. Cardiol., January 7, 2004; 43(1): 55 - 60. [Abstract] [Full Text] [PDF] |
||||
![]() |
I Raymond, F Pedersen, F Steensgaard-Hansen, A Green, M Busch-Sorensen, C Tuxen, J Appel, J Jacobsen, D Atar, and P Hildebrandt Prevalence of impaired left ventricular systolic function and heart failure in a middle aged and elderly urban population segment of Copenhagen Heart, December 1, 2003; 89(12): 1422 - 1429. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. M. Pritchett, S. J. Jacobsen, D. W. Mahoney, R. J. Rodeheffer, K. R. Bailey, and M. M. Redfield Left atrial volume as an index ofleft atrial size: a population-based study J. Am. Coll. Cardiol., March 19, 2003; 41(6): 1036 - 1043. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Shimoni, N. G. Frangogiannis, C. J. Aggeli, K. Shan, M. S. Verani, M. A. Quinones, R. Espada, G. V. Letsou, G. M. Lawrie, W. L. Winters, et al. Identification of Hibernating Myocardium With Quantitative Intravenous Myocardial Contrast Echocardiography: Comparison With Dobutamine Echocardiography and Thallium-201 Scintigraphy Circulation, February 4, 2003; 107(4): 538 - 544. [Abstract] [Full Text] [PDF] |
||||
![]() |
V. T. Nkomo, M. Enriquez-Sarano, N. M. Ammash, L. J. Melton III, K. R. Bailey, V. Desjardins, R. A. Horn, and A. J. Tajik Bicuspid Aortic Valve Associated With Aortic Dilatation: A Community-Based Study Arterioscler. Thromb. Vasc. Biol., February 1, 2003; 23(2): 351 - 356. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. M. Redfield, S. J. Jacobsen, J. C. Burnett Jr, D. W. Mahoney, K. R. Bailey, and R. J. Rodeheffer Burden of Systolic and Diastolic Ventricular Dysfunction in the Community: Appreciating the Scope of the Heart Failure Epidemic JAMA, January 8, 2003; 289(2): 194 - 202. [Abstract] [Full Text] [PDF] |
||||
![]() |
J.-F. Avierinos, B. J. Gersh, L. J. Melton III, K. R. Bailey, C. Shub, R. A. Nishimura, A. J. Tajik, and M. Enriquez-Sarano Natural History of Asymptomatic Mitral Valve Prolapse in the Community Circulation, September 10, 2002; 106(11): 1355 - 1361. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Shimoni, N. G. Frangogiannis, C. J. Aggeli, K. Shan, M. A. Quinones, R. Espada, G. V. Letsou, G. M. Lawrie, W. L. Winters, M. J. Reardon, et al. Microvascular Structural Correlates of Myocardial Contrast Echocardiography in Patients With Coronary Artery Disease and Left Ventricular Dysfunction: Implications for the Assessment of Myocardial Hibernation Circulation, August 20, 2002; 106(8): 950 - 956. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. A. Nishimura, J. A. Grantham, H. M. Connolly, H. V. Schaff, S. T. Higano, and D. R. Holmes Jr Low-Output, Low-Gradient Aortic Stenosis in Patients With Depressed Left Ventricular Systolic Function: The Clinical Utility of the Dobutamine Challenge in the Catheterization Laboratory Circulation, August 13, 2002; 106(7): 809 - 813. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Colao, C. Di Somma, M. Salerno, L. Spinelli, F. Orio, and G. Lombardi The Cardiovascular Risk of GH-Deficient Adolescents J. Clin. Endocrinol. Metab., August 1, 2002; 87(8): 3650 - 3655. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Grigioni, J.-F. Avierinos, L. H. Ling, C. G. Scott, K. R. Bailey, A. J. Tajik, R. L. Frye, and M. Enriquez-Sarano Atrial fibrillation complicating the course of degenerative mitral regurgitation: Determinants and long-term outcome J. Am. Coll. Cardiol., July 3, 2002; 40(1): 84 - 92. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. M. Fleming A Tete-a-Tete Comparison of Ejection Fraction and Regional Wall Motion Abnormalities as Measured by Echocardiography and Gated Sestamibi SPECT Angiology, May 1, 2002; 53(3): 313 - 321. [Abstract] [PDF] |
||||
![]() |
O W Nielsen, J Hilden, C T Larsen, and J F Hansen Cross sectional study estimating prevalence of heart failure and left ventricular systolic dysfunction in community patients at risk Heart, August 1, 2001; 86(2): 172 - 178. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Y.T. Hart, D. M. Meyer, H. D. Tazelaar, J. P. Grande, J. C. Burnett Jr, P. R. Housmans, and M. M. Redfield Load Versus Humoral Activation in the Genesis of Early Hypertensive Heart Disease Circulation, July 10, 2001; 104(2): 215 - 220. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Tabata, S. S. Kabbani, R. D. Murray, J. D. Thomas, I. Abdalla, and A. L. Klein Difference in the respiratory variation between pulmonary venous and mitral inflow doppler velocities in patients with constrictive pericarditis with and without atrial fibrillation J. Am. Coll. Cardiol., June 1, 2001; 37(7): 1936 - 1942. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. F. Nagueh, S. J. Stetson, N. M. Lakkis, D. Killip, A. Perez-Verdia, M. L. Entman, W. H. Spencer III, and G. Torre-Amione Decreased Expression of Tumor Necrosis Factor-{{alpha}} and Regression of Hypertrophy After Nonsurgical Septal Reduction Therapy for Patients With Hypertrophic Obstructive Cardiomyopathy Circulation, April 10, 2001; 103(14): 1844 - 1850. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Grigioni, M. Enriquez-Sarano, K. J. Zehr, K. R. Bailey, and A. J. Tajik Ischemic Mitral Regurgitation : Long-Term Outcome and Prognostic Implications With Quantitative Doppler Assessment Circulation, April 3, 2001; 103(13): 1759 - 1764. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Shan, R. J. Bick, B. J. Poindexter, S. F. Nagueh, S. Shimoni, M. S. Verani, F. Keng, M. J. Reardon, G. V. Letsou, J. F. Howell, et al. Altered Adrenergic Receptor Density in Myocardial Hibernation in Humans : A Possible Mechanism of Depressed Myocardial Function Circulation, November 21, 2000; 102(21): 2599 - 2606. [Abstract] [Full Text] [PDF] |
||||
![]() |
C Bruch, A Schmermund, D Marin, M Katz, T Bartel, J Schaar, and R Erbel Tei-Index in patients with mild-to-moderate congestive heart failure Eur. Heart J., November 2, 2000; 21(22): 1888 - 1895. [Abstract] [PDF] |
||||
![]() |
A. J. Rainbird, P. A. Pellikka, V. L. Stussy, D. M. Mahoney, and J. B. Seward A rapid stress-testing protocol for the detection of coronary artery disease: Comparison of two-stage transesophageal atrial pacing stress echocardiography with dobutamine stress echocardiography J. Am. Coll. Cardiol., November 1, 2000; 36(5): 1659 - 1663. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Luchner, M. Jougasaki, E. Friedrich, D. D. Borgeson, T. L. Stevens, M. M. Redfield, G. A. J. Riegger, and J. C. Burnett Jr. Activation of cardiorenal and pulmonary tissue endothelin-1 in experimental heart failure Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2000; 279(3): R974 - R979. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. K. Das, P. A. Pellikka, D. W. Mahoney, V. L. Roger, J. K. Oh, R. B. McCully, and J. B. Seward Assessment of cardiac risk before nonvascular surgery: Dobutamine stress echocardiography in 530 patients J. Am. Coll. Cardiol., May 1, 2000; 35(6): 1647 - 1653. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. M. Connolly, J. K. Oh, H. V. Schaff, V. L. Roger, S. L. Osborn, D. O. Hodge, and A. J. Tajik Severe Aortic Stenosis With Low Transvalvular Gradient and Severe Left Ventricular Dysfunction : Result of Aortic Valve Replacement in 52 Patients Circulation, April 25, 2000; 101(16): 1940 - 1946. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. M. Cwajg, E. Cwajg, S. F. Nagueh, Z.-X. He, U. Qureshi, L. I. Olmos, M. A. Quinones, M. S. Verani, W. L. Winters, and W. A. Zoghbi End-diastolic wall thickness as a predictor of recovery of function in myocardial hibernation: Relation to rest-redistribution Tl-201 tomography and dobutamine stress echocardiography J. Am. Coll. Cardiol., April 1, 2000; 35(5): 1152 - 1161. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. A. Quinones, B. H. Greenberg, H. A. Kopelen, C. Koilpillai, M. C. Limacher, D. M. Shindler, B. J. Shelton, D. H. Weiner, and for the SOLVD Investigators Echocardiographic predictors of clinical outcome in patients with left ventricular dysfunction enrolled in the SOLVD registry and trials: significance of left ventricular hypertrophy J. Am. Coll. Cardiol., April 1, 2000; 35(5): 1237 - 1244. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. L. Milavetz, S. N. Hayes, S. A. Weston, J. B. Seward, C. J. Mullany, and V. L. Roger Sex Differences in Left Ventricular Geometry in Aortic Stenosis: Impact on Outcome Chest, April 1, 2000; 117(4): 1094 - 1099. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Giunta, E. Tirri, S. Maione, S. Cangianiello, A. Mele, A. De Luca, and G. Valentini Right ventricular diastolic abnormalities in systemic sclerosis. Relation to left ventricular involvement and pulmonary hypertension Ann Rheum Dis, February 1, 2000; 59(2): 94 - 98. [Abstract] [Full Text] |
||||
![]() |
|