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Circulation. 1977;55:767-772

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Circulation, Vol 55, 767-772, Copyright © 1977 by American Heart Association


ARTICLES

HDL cholesterol and other lipids in coronary heart disease. The cooperative lipoprotein phenotyping study

WP Castelli, JT Doyle, T Gordon, CG Hames, MC Hjortland, SB Hulley, A Kagan and WJ Zukel

The relation between coronary heart disease (CHD) prevalence and fasting lipid levels was assessed by a case-control study in five populations with a total of 6859 men and women of black, Japanese and white ancestry drawn from subjects aged 40 years and older from populations in Albany, Framingham, Evans County, Honolulu and San Francisco. In each major study group mean levels of high density lipoprotein (HDL) cholesterol were lower in persons with CHD than in those without the disease. The average difference was small -- typically 3-4 mg/dl -- but statistically significant. It was found in most age-race-sex specific groups. The inverse HDL cholesterol-CHD association was not appreciably diminished when adjusted for levels of low density lipoprotein (LDL) cholesterol and triglyceride. LDL, totoal cholesterol and triglycerides were directly related to CHD prevalence; surprisingly, these findings were less uniformly present in the various study groups than the inverse HDL cholesterol-CHD association.


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T. J. Vecchio, C. V. Linden, M. J. O'Connell, and J. Heilman
Comparative Efficacy of Colestipol and Clofibrate in Type IIa Hyperlipoproteinemia
Arch Intern Med, April 1, 1982; 142(4): 721 - 723.
[Abstract] [PDF]


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Arch Intern MedHome page
I. Lipinska and V. Gurewich
The Value of Measuring Percent High-Density Lipoprotein in Assessing Risk of Cardiovascular Disease
Arch Intern Med, March 1, 1982; 142(3): 469 - 472.
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ANN INTERN MEDHome page
P. DOUSTE-BLAZY, Y. L. MARCEL, L. COHEN, J.-M. GIROUX, and J. DAVIGNON
Increased Frequency of Apo E-ND Phenotype and Hyperapobetalipoproteinemia in Normolipidemic Subjects with Xanthelasmas of the Eyelids
Ann Intern Med, February 1, 1982; 96(2): 164 - 169.
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Arch Intern MedHome page
K. D. Brownell and A. J. Stunkard
Differential Changes in Plasma High-Density Lipoprotein-Cholesterol Levels in Obese Men and Women During Weight Reduction
Arch Intern Med, August 1, 1981; 141(9): 1142 - 1146.
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JAMAHome page
J. A. Morrison, P. Khoury, M. Mellies, K. Kelly, R. Horvitz, and C. J. Glueck
Lipid and Lipoprotein Distributions in Black Adults: The Cincinnati Lipid Research Clinic's Princeton School Study
JAMA, March 6, 1981; 245(9): 939 - 942.
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JAMAHome page
P. L. Hooper, L. Visconti, P. J. Garry, and G. E. Johnson
Zinc Lowers High-Density Lipoprotein-Cholesterol Levels
JAMA, October 24, 1980; 244(17): 1960 - 1961.
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ANN INTERN MEDHome page
E. J. SCHAEFER, L. A. ZECH, D. E. SCHWARTZ, and H. B. BREWER Jr.
Coronary Heart Disease Prevalence and Other Clinical Features in Familial High-Density Lipoprotein Deficiency (Tangier Disease)
Ann Intern Med, August 1, 1980; 93(2): 261 - 266.
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Arch Intern MedHome page
A. Zampogna, M. H. Luria, S. J. Manubens, and M. A. Luria
Relationship Between Lipids and Occlusive Coronary Artery Disease
Arch Intern Med, August 1, 1980; 140(8): 1067 - 1069.
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JAMAHome page
D. W. Erkelens, J. J. Albers, W. R. Hazzard, R. C. Frederick, and E. L. Bierman
High-Density Lipoprotein-Cholesterol in Survivors of Myocardial Infarction
JAMA, November 16, 1979; 242(20): 2185 - 2189.
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D. Streja and D. Mymin
Moderate Exercise and High-Density Lipoprotein-Cholesterol: Observations During a Cardiac Rehabilitation Program
JAMA, November 16, 1979; 242(20): 2190 - 2192.
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JAMAHome page
R. L. Landau
What You Should Know About Estrogens: Or the Perils of Pauline
JAMA, January 5, 1979; 241(1): 47 - 51.
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ANN INTERN MEDHome page
W. B. KANNEL, W. P. CASTELLI, and T. GORDON
Cholesterol in the Prediction of Atherosclerotic Disease: New Perspectives Based on the Framingham Study
Ann Intern Med, January 1, 1979; 90(1): 85 - 91.
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ANN INTERN MEDHome page
D. STREJA, G. STEINER, and P. O. KWITEROVICH Jr.
Plasma High-Density Lipoproteins and Ischemic Heart Disease: Studies in a Large Kindred with Familial Hypercholesterolemia
Ann Intern Med, December 1, 1978; 89(6): 871 - 880.
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JAMAHome page
S. B. Hulley, R. Cohen, and G. Widdowson
Plasma High-Density Lipoprotein Cholesterol Level: Influence of Risk Factor Intervention
JAMA, November 21, 1977; 238(21): 2269 - 2271.
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ANN INTERN MEDHome page
T. GORDON, W. P. CASTELLI, M. C. HJORTLAND, W. B. KANNEL, and T. R. DAWBER
Diabetes, Blood Lipids, and the Role of Obesity in Coronary Heart Disease Risk for Women: The Framingham Study
Ann Intern Med, October 1, 1977; 87(4): 393 - 397.
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J. Biol. Chem.Home page
Y. Ueda, E. Gong, L. Royer, P. N. Cooper, O. L. Francone, and E. M. Rubin
Relationship between Expression Levels and Atherogenesis in Scavenger Receptor Class B, Type I Transgenics
J. Biol. Chem., June 30, 2000; 275(27): 20368 - 20373.
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J. Biol. Chem.Home page
H.-Y. Kan, S. Georgopoulos, and V. Zannis
A Hormone Response Element in the Human Apolipoprotein CIII (ApoCIII) Enhancer Is Essential for Intestinal Expression of the ApoA-I and ApoCIII Genes and Contributes to the Hepatic Expression of the Two Linked Genes in Transgenic Mice
J. Biol. Chem., September 22, 2000; 275(39): 30423 - 30431.
[Abstract] [Full Text] [PDF]