Circulation, Vol 54, 837-843, Copyright © 1976 by American Heart Association
GS Orsmond, L Knight, LP Dehner, DM Nicoloff, M Nesbitt and FB Bessinger Jr
A 12-year-old girl, who had had an above-knee amputation of the left leg
for a soft tissue sarcoma six years prior to this admission, presented with
syncope, angina, and signs of aortic stenosis. Echocardiography
demonstrated a mass arising from the interventricular septum with
obstruction of the left ventricular outflow tract and aortic valve. Cardiac
catheterization and angiography confirmed these findings. At operation, a
tumor was found involving the interventricular septum. Histologically, it
was an alveolar rhabdomyosarcoma, and it appeared similar to the previous
tumor. The patient was treated by partial surgical resection, cytotoxic
drugs and localized radiation therapy and has been followed by serial
echocardiography.
ARTICLES
Alveolar rhabdomyosarcoma involving the heart. An echocardiographic, angiographic and pathologic study
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