Circulation. 2008;117:e25-e146
Published online before print December 17, 2007,
doi: 10.1161/CIRCULATIONAHA.107.187998
(Circulation. 2008;117:e25-e146.)
© 2008 American Heart Association, Inc.
Heart Disease and Stroke Statistics—2008 Update
A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Writing Group: Wayne Rosamond, PhD, FAHA;
Katherine Flegal, PhD*;
Karen Furie, MD;
Alan Go, MD;
Kurt Greenlund, PhD*;
Nancy Haase;
Susan M. Hailpern, DrPH, MS;
Michael Ho, MD, PhD;
Virginia Howard, MSPH, FAHA;
Bret Kissela, MD;
Steven Kittner, MD;
Donald Lloyd-Jones, MD, FAHA;
Mary McDermott, MD;
James Meigs, MD;
Claudia Moy, PhD;
Graham Nichol, MD;
Christopher ODonnell, MD, MPH, FAHA;
Veronique Roger, MD;
Paul Sorlie, PhD;
Julia Steinberger, MD, MSC;
Thomas Thom;
Matt Wilson, MD;
Yuling Hong, MD, PhD, FAHA, for the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
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Table of Contents
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- Summary...e26
- 1. About These Statistics...e28
- 2. Cardiovascular Diseases...e31
- 3. Coronary Heart Disease, Acute Coronary Syndrome, and Angina Pectoris...e50
- 4. Stroke...e61
- 5. High Blood Pressure...e76
- 6. Congenital Cardiovascular Defects...e82
- 7. Heart Failure...e86
- 8. Other Cardiovascular Diseases...e90
- — Arrhythmias (Disorders of Heart Rhythm)...e90
- — Arteries, Diseases of (Including Peripheral Arterial Disease)...e91
- — Bacterial Endocarditis...e92
- — Cardiomyopathy...e93
- — Rheumatic Fever/Rheumatic Heart Disease...e93
- — Valvular Heart Disease...e93
- — Venous Thromboembolism...e93
- 9. Risk Factor: Smoking/Tobacco Use...e97
- 10. Risk Factor: High Blood Cholesterol and Other Lipids...e102
- 11. Risk Factor: Physical Inactivity...e106
- 12. Risk Factor: Overweight and Obesity...e109
- 13. Risk Factor: Diabetes Mellitus...e113
- 14. End-Stage Renal Disease and Chronic Kidney Disease...e120
- 15. Metabolic Syndrome...e123
- 16. Nutrition...e125
- 17. Quality of Care...e128
- 18. Medical Procedures...e133
- 19. Economic Cost of Cardiovascular Diseases...e137
- 20. At-a-Glance Summary Tables...e139
- — Males and Cardiovascular Diseases...e139
- — Females and Cardiovascular Diseases...e140
- — Ethnic Groups and Cardiovascular Diseases...e141
- — Children, Youth, and Cardiovascular Diseases...e142
- 21. Glossary ...e143
- Disclosures...e146
- Appendix I: List of Statistical Fact Sheets. URL: http://www.americanheart.org/presenter.jhtml?identifier=2007
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Acknowledgments
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We thank Drs Robert Adams, Gary Friday, Philip Gorelick, and
Sylvia Wasserthiel-Smoller, members of Stroke Statistics Subcommittee;
Drs Joe Broderick, Brian Eigel, Kimberlee Gauveau, Jane Khoury,
Jerry Potts, Jane Newburger, and Kathryn Taubert; and Sean Coady
and Michael Wolz for their valuable comments and contributions.
We acknowledge Tim Anderson and Tom Schneider for their editorial
contributions and Karen Modesitt for her administrative assistance.
Summary
Each year the American Heart Association, in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics on heart disease, stroke, and their risk factors and presents them in its Heart Disease and Stroke Statistical Update. The Statistical Update is a valuable resource for researchers, clinicians, healthcare policy makers, media, the lay public, and many others who seek the best national data available on disease and risk factor prevalence, disease incidence, and mortality rates in a single document. This years edition includes several areas not covered in previous editions. Below are a few highlights from this years Update in the areas of cardiovascular disease (CVD) mortality, control of risk factors, kidney disease, and medical care.
Death rates from CVD have declined, yet the burden of disease remains high.
- The 2004 overall death rate from CVD (International Classification of Diseases 10, I00–I99) was 288.0 per 100 000. The rates were 335.1 per 100 000 for white males, 454.0 per 100 000 for black males, 238.0 per 100 000 for white females, and 333.6 per 100 000 for black females. From 1994 to 2004, death rates from CVD (International Classification of Diseases 10, I00–I99) declined 24.7%. Preliminary mortality data from 2005 show that CVD (I00–I99; Q20–Q28) accounted for 35.2% (861 826) of all 2 447 910 deaths in 2005, or 1 of every 2.8 deaths in the United States.
- Nearly 2400 Americans die of CVD each day—an average of 1 death every 37 seconds. The 2005 overall preliminary death rate from CVD was 279.2. More than 148 000 Americans killed by CVD (I00–I99) in 2004 were <65 years of age. In 2004, 32% of deaths from CVD occurred before the age of 75 years, which is well before the average life expectancy of 77.9 years.
- Coronary heart disease caused 1 of every 5 deaths in the United States in 2004. Coronary heart disease mortality was 451 326. In 2008, an estimated 770 000 Americans will have a new coronary attack, and about 430 000 will have a recurrent attack. It is estimated that an additional 175 000 silent first myocardial infarctions occur each year. About every 26 seconds, an American will have a coronary event, and about every minute someone will die from one.
- Each year, about 780 000 people experience a new or recurrent stroke. About 600 000 of these are first attacks, and 180 000 are recurrent attacks. Preliminary data from 2005 indicate that stroke accounted for about 1 of every 17 deaths in the United States. On average, every 40 seconds someone in the United States has a stroke. From 1994 to 2004, the stroke death rate fell 24.2%, and the actual number of stroke deaths declined 6.8%.
- In 2004, 1 in 8 death certificates (284 365 deaths) in the United States mentions heart failure.
Control of risk factors remains an issue for many Americans.
- The age-adjusted prevalence of high low-density lipoprotein cholesterol in US adults was 26.6% in 1988–1994 and 25.3% in 1999–2004. Between 1988–1994 and 1999–2004, awareness increased from 39.2% to 63.0%, and use of pharmacological lipid-lowering treatment increased from 11.7% to 40.8%. Low-density lipoprotein cholesterol control increased from 4.0% to 25.1% among those with high low-density lipoprotein cholesterol.
- Overall, 62.0% of adults
18 years of age engaged in at least some vigorous and/or light-moderate leisure-time physical activity lasting
10 minutes per session. In 2002–2004, 40.2% of people
75 years of age (age adjusted) engaged in at least some regular leisure-time physical activity. Men were more likely (64.0%) to exercise than were women (60.2%).
- More than 9 million children and adolescents between 6 and 19 years of age are considered overweight on the basis of being in the 95th percentile or higher of body mass index values in the 2000 Centers for Disease Control and Prevention growth chart.
- On the basis of data from the National Health and Nutrition Examination Survey, the prevalence of overweight in children between 6 and 11 years of age increased from 4.0% in 1971–1974 to 17.5% in 2001–2004. The prevalence of overweight in adolescents between 12 and 19 years of age increased from 6.1% to 17.0%. In 2003–2004, 36% of women 65 to 74 years of age and 24% of women
75 years of age were obese. This is an increase from 1988–1994, when 27% of women 65 to 74 years of age and 19% of women
75 years of age were obese. For men, from 1988–1994, 24% of those 65 to 74 years of age and 13% of those
75 years of age were obese, compared with 33% of those 65 to 74 years of age and 23% of those
75 years of age in 2003–2004.
- One and a half million new cases of diabetes were diagnosed in people
20 years of age in 2005.
The 2008 Update expands data coverage of CVD-related kidney disease.
- End-stage renal disease and chronic kidney disease are conditions that are most commonly associated with diabetes and/or high blood pressure and occur when the kidneys can no longer function normally on their own.
- The incidence of reported end-stage renal disease has almost doubled in the past 10 years. In 2004, 104 364 new cases of end-stage renal disease were reported.
- The number of persons treated for end-stage renal disease increased from 68 757 in 1994 to 102 356 in 2004; this translates to 261.3 per million in 1994 to 348.6 per million in 2004.
- The US Renal Data System estimates that by 2010, 650 000 Americans will require treatment for kidney failure, which represents a 60% increase over the number who received such treatment in 2001.
- The prevalence of chronic kidney disease (stages I–V) is 16.8%. This represents an increase over the 14.5% prevalence estimate from the National Health and Nutrition Examination Survey 1988–1994.
- The prevalence of chronic kidney disease was greater among those with diabetes (40.2%), hypertension (24.6%), and CVD (28.2%) than among those without these chronic conditions.
Improvements in medical care are being made.
- Over a 3-year period from 2002 through 2004, among 159 168 patients admitted with heart failure at 285 hospitals, inotrope use decreased, and improvements were made in providing discharge instructions, smoking counseling, left ventricular assessment, and β-blocker prescription.
- During this same period of time, clinical outcomes improved, including the need for mechanical ventilation (5.3% to 3.4%), length of stay (mean, 6.3 days to 5.5 days), and in-hospital death rate (4.5% to 3.2%).
The American Heart Association, through its Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States to provide the most current data available in the Statistics Update. The 2005 preliminary mortality data have been released, and although not included in this years Update, more information can be found at the National Center for Health Statistics Web site, http://www.cdc.gov/nchs/products/pubs/pubd/hestats/prelimdeaths05/prelimdeaths05.htm.
1. About These Statistics
The American Heart Association (AHA) works with the Centers for Disease Control and Preventions National Center for Health Statistics (CDC/NCHS); the National Heart, Lung, and Blood Institute (NHLBI); the National Institute of Neurological Disorders and Stroke (NINDS); and other government agencies to derive the annual statistics in this Update. This chapter describes the most important sources and the types of data we use from them. For more details and an alphabetical list of abbreviations, see Chapter 21 of this document, the Glossary and Abbreviation Guide.
The surveys used are:
- Behavioral Risk Factor Surveillance Survey (BRFSS)—ongoing telephone health survey system
- Greater Cincinnati/Northern Kentucky Stroke Study (GCNKSS)—stroke incidence rates and outcome within a biracial population
- Medical Expenditure Panel Survey (MEPS)—data on specific health services that Americans use, how frequently they use them, the cost of these services, and how they are paid for
- National Health and Nutrition Examination Survey (NHANES)—disease and risk factor prevalence and nutrition statistics
- National Health Interview Survey (NHIS)—disease and risk factor prevalence
- National Hospital Discharge Survey (NHDS)—hospital inpatient discharges (discharged alive, dead, or status unknown)
- National Ambulatory Medical Care Survey (NAMCS)—physician office visits
- National Hospital Ambulatory Medical Care Survey (NHAMCS)—hospital outpatient and emergency department visits
- National Inpatient Sample (NIS) of the Agency for Health Research and Quality—hospital inpatient discharges and charges
- National Institute of Neurological Disorders and Stroke (NINDS)—brain and nervous system disorders
- National Nursing Home Survey (NNHS)—nursing home visits
- National Vital Statistics—national and state mortality data
- World Health Organization (WHO)—country mortality
- Youth Risk Behavior Surveillance (YRBS)—trends for 6 categories of priority health-risk behaviors in youth and young adults
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Disease Prevalence
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Prevalence is an estimate of how many people have a disease
at a given point or period in time. The NCHS conducts health
examination and health interview surveys that provide estimates
of the prevalence of diseases and risk factors. In this Update,
the health interview part of the NHANES is used for the prevalence
of cardiovascular diseases (CVD). NHANES is used more than the
NHIS because in NHANES, angina pectoris (AP) is based on the
Rose Questionnaire; estimates are made regularly for heart failure
(HF); hypertension is based on blood pressure (BP) measurements
and interviews; and an estimate can be made of total CVD to
include myocardial infarction (MI), AP, HF, stroke, and hypertension.
A major emphasis of this Update is to present the latest estimates of the number of persons in the United States who have specific conditions in order to provide a more realistic estimate of burden. Most estimates based on NHANES prevalence rates use data collected from 1999 to 2004 (in most cases, these are the latest published figures). These are applied to census population estimates for 2005. Differences in population estimates based on extrapolations of rates beyond the data collection period by using more recent census population estimates cannot be used to evaluate possible trends in prevalence. Trends can only be evaluated by comparing prevalence rates estimated from surveys conducted in different years.
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Risk Factor Prevalence
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The NHANES 1999–2004 data are used in this Update to present
estimates of the percentage of persons with high lipid values,
diabetes, overweight, and obesity. The NHIS is used for the
prevalence of cigarette smoking and physical inactivity. Data
for students in grades 9 through 12 are obtained from the Youth
Risk Factor Surveillance System.
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Incidence and Recurrent Attacks
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An incidence rate refers to the number of new cases of a disease
that develop in a population per unit of time. The unit of time
is not necessarily 1 year, although we often discuss incidence
in terms of 1 year. For some statistics, new and recurrent attacks
or cases are combined. Our national incidence estimates for
the various types of CVD are extrapolations to the US population
from the Framingham Heart Study (FHS), the Atherosclerosis Risk
in Communities (ARIC) study, the Cardiovascular Health Study
(CHS) conducted by the NHLBI, and the Greater Cincinnati/Northern
Kentucky Stroke Study (GCNKSS) funded by the NINDS. The rates
change only when new data are available; they are not computed
annually. Do not compare the incidence or the rates with those
in past editions of the Heart and Stroke Statistical Update
(renamed the Heart Disease and Stroke Statistics Update). Doing
so can lead to serious misinterpretation of time trends.
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Mortality
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Mortality data are grouped according to the underlying cause
of death. "Total-mention" mortality is the number of death certificates
in 2004 that mention the given disease classification either
as the underlying cause or as a contributing cause. These were
final 2004 data unless otherwise indicated. For many deaths
classified as attributable to CVD, selection of the most likely
single underlying cause can be difficult when several major
comorbidities are present, as is often the case in the elderly
population. It is, therefore, useful to know the extent of mortality
from a given cause, regardless of whether it is the underlying
cause or a contributing cause—ie, its "total mentions."
In all comparisons of deaths and death rates between 1994 and
2004, 1994 data were modified using appropriate comparability
ratios.
The first text section for each disease listed in this Update mentions mortality information. This includes the number of deaths for which the disease is the underlying cause; this is referred to as "mortality." That number is followed by "total-mention mortality." All other numbers or rates of deaths in the Update refer to the given disease as the underlying cause. The one exception, heart failure, is explained in that section.
National and state mortality data presented according to the underlying cause of death are computed from the Data Warehouse morta