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(Circulation. 2007;115:e56-e59.)
© 2007 American Heart Association, Inc.

Clinician Update

Apical Ballooning Syndrome

An Important Differential Diagnosis of Acute Myocardial Infarction

Abhiram Prasad, MD, FRCP, FESC

From the Division of Cardiovascular Diseases and Department of Internal Medicine, and Mayo Clinic and Mayo Foundation, Rochester, Minn.

Reprint requests to Abhiram Prasad, MD, Cardiac Catheterization Laboratory, Mayo Clinic, 200 First St SW, Rochester, MN 55905. E-mail prasad.abhiram@mayo.edu

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	Introduction

 
Case presentation: A 60-year-old woman presented to the emergency department 2 hours after the onset of severe retrosternal chest pain that started soon after she was told that her son had died in a car accident. A 12-lead ECG demonstrated ST-elevation in the precordial leads (Figure 1), and the plasma troponin T level was elevated at 0.07 ng/mL. A diagnosis of acute ST-elevation myocardial infarction was made, and the patient was admitted for emergency coronary angiography, which revealed normal coronary arteries. The left ventriculogram showed severe systolic dysfunction involving the mid and apical segments (Data Supplement Movie I).

View larger version (25K):   Figure 1. Twelve-lead ECG demonstrating ST-segment elevation in precordial leads.

	Recognition of Clinical Syndrome

 
Physicians have long been aware of the possible association between stress and cardiovascular events. Awareness has increased of a distinct cardiac syndrome that was originally described in the Japanese population and was called Takotsubo cardiomyopathy, named after the octopus-trapping pot with a round bottom and narrow neck that resembles the left ventriculogram during systole in these patients.^1,2 Other names used to describe the condition include apical ballooning syndrome (ABS), broken heart syndrome, and stress or ampulla cardiomyopathy. The precise incidence of ABS is unknown, but it may account for 1% to 2% of patients who present with an acute myocardial infarction.³

	Clinical Features

 
The majority of patients have a clinical presentation that is indistinguishable from an acute coronary syndrome. Most present with chest pain at rest, although some patients have dyspnea alone as their initial presenting symptom. Rarely, patients present with syncope . . . [Full Text of this Article]

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