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Circulation. 2006;114:867-868
doi: 10.1161/CIRCULATIONAHA.106.645572
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(Circulation. 2006;114:867-868.)
© 2006 American Heart Association, Inc.


In Memoriam

Carl S. Apstein, MD

1941–2005

Laura Wexler, MD; Joanne S. Ingwall, PhD

From the University of Cincinnati College of Medicine, Cincinnati, Ohio (L.W.), and Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass (J.S.I.).

Correspondence to Laura F. Wexler, Associate Dean, Student Affairs and Admissions, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Medical Science Building, Room E251, Cincinnati, Ohio 45267-0552. E-mail Wexler@ucmail.uc.edu


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Carl S. Apstein, Professor of Medicine and Physiology and founder of the Cardiac Muscle Research Laboratory at Boston University School of Medicine died November 8, 2005, after a year-long battle with pancreatic cancer. He was 64.

Carl was born in Brooklyn, NY, and did his undergraduate work at Cornell University, where he was a Telluride Scholar. He graduated from New York University School of Medicine in 1967. After his internal medicine residency and cardiology fellowship at New York Hospital–Cornell Medical Center, he received additional research fellowships at Tufts New England Medical Center and the Massachusetts Institute of Technology. He joined the faculty of Boston University School of Medicine in 1973, where he founded the Cardiac Muscle Research Laboratory, a continuously productive laboratory and highly regarded training site for investigators from all over the world. He also served as Chief of Cardiology at Boston City Hospital from 1982 to 1996.


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Dr Apstein was an outstanding investigator, a great clinician, and a revered teacher and mentor. As a clinician, he was known for his superb physical examination skills, for his astute diagnostic acumen, and particularly for his wonderful ability to teach pathophysiology and mechanisms of disease. His weekly clinical case rounds at Boston City Hospital were eagerly attended by the entire division and serve as models of the kind of cheerfully provocative Socratic teaching and discussion that characterize a true "Master Teacher," one who was able to bring basic mechanisms of disease discovered in the laboratory into exciting clinical reality.

Dr Apstein . . . [Full Text of this Article]