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(Circulation. 2006;114:1761-1791.)
© 2006 American Heart Association, Inc.

AHA Scientific Statement

Assessment of Coronary Artery Disease by Cardiac Computed Tomography

A Scientific Statement From the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Cardiology

Matthew J. Budoff, MD, FAHA; Stephan Achenbach, MD; Roger S. Blumenthal, MD, FAHA; J. Jeffrey Carr, MD, MSCE; Jonathan G. Goldin, MD, PhD; Philip Greenland, MD, FAHA; Alan D. Guerci, MD; Joao A.C. Lima, MD, FAHA; Daniel J. Rader, MD, FAHA; Geoffrey D. Rubin, MD; Leslee J. Shaw, PhD; Susan E. Wiegers, MD

Key Words: AHA Scientific Statements • calcium • atherosclerosis • coronary disease • noninvasive coronary angiography

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	TABLE OF CONTENTS

 

Executive Summary...1761

Introduction...1764

1. Coronary Artery Calcification and Epidemiology of Coronary Calcium...1764

   1.1. Calcium Detection Methods ...1765

      1.1.1. EBCT Methods...1765

      1.1.2. MDCT Methods ...1766

   1.2. Coronary Artery Calcified Plaque ...1766

   1.3. Speed/Temporal Resolution...1767

   1.4. Studies Comparing EBCT and MDCT for Calcium Scoring...1767

   1.5. Reproducibility and Validity of Calcium Scoring ...1767

   1.6. Radiation Dose for Cardiac CT...1768

      1.6.1. Radiation Exposure During CT Angiography ...1769

2. Clinical Utility of CACP Detection ...1771

   2.1. CT Coronary Calcium and Symptomatic Patients...1771

   2.2. CT Coronary Calcification and Clinical Outcomes in Asymptomatic Individuals...1772

   2.3. Limitations...1774

   2.4. Recommendations of Professional Societies...1775

   2.5. Utilizing Coronary Calcium Measure to Improve Outcomes...1776

   2.6. Limitations of the Use of Coronary Calcium for Detecting Obstructive Disease in Asymptomatic Persons ...1777

3. Future Directions...1777

   3.1. Tracking Progression of Subclinical Atherosclerosis...1777

   3.2. Hybrid Nuclear/CT Imaging ...1779

   3.3. Contrast-Enhanced CT of the Coronary Arteries...1779

      3.3.1. Electron Beam CT ...1779

      3.3.2. Multidetector CT ...1780

   3.4. CT Angiography Applications in a Clinical Context...1782

      3.4.1. Suspected CAD...1782

      3.4.2. Follow-Up of Percutaneous Coronary Intervention...1782

      3.4.3. Follow-Up After Bypass Surgery...1782

      3.4.4. Anomalous Coronary Arteries ...1782

   3.5. Assessment of NCP ...1782

Conclusion ...1783

Disclosures ...1784

References ...1784

	Executive Summary

 
This scientific statement reviews the scientific data for cardiac computed tomography (CT) related to imaging of coronary artery disease (CAD) and atherosclerosis. Cardiac CT is a CT imaging technique that accounts for cardiac motion, typically through the use of ECG gating. The utility and limitations of generations of cardiac CT systems are reviewed in this statement with emphasis on CT measurement of CAD and . . . [Full Text of this Article]

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				A. J. Einstein, M. J. Henzlova, and S. Rajagopalan Estimating Risk of Cancer Associated With Radiation Exposure From 64-Slice Computed Tomography Coronary Angiography JAMA, July 18, 2007; 298(3): 317 - 323. [Abstract] [Full Text] [PDF]

				W. Koenig Cardiovascular Biomarkers: Added Value With an Integrated Approach? Circulation, July 3, 2007; 116(1): 3 - 5. [Full Text] [PDF]

				G. Hur, S. W. Hong, S. Y. Kim, Y. H. Kim, Y. J. Hwang, W. R. Lee, and S. J. Cha Uniform Image Quality Achieved by Tube Current Modulation Using SD of Attenuation in Coronary CT Angiography Am. J. Roentgenol., July 1, 2007; 189(1): 188 - 196. [Abstract] [Full Text] [PDF]

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				K. Nasir, A. Roguin, A. Sarwar, J. A. Rumberger, and R. S. Blumenthal Letter to the Editor: Gender Differences in Coronary Arteries and Thoracic Aorta Calcification Arterioscler. Thromb. Vasc. Biol., May 1, 2007; 27(5): 1220 - 1222. [Full Text] [PDF]

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